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Can One Continue Metformin During Pregnancy?

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Posted on Wed, 23 Nov 2016
Question: Hi Doctor, My wife is conceived since 1 month and its going to be our second baby. She's having type -2 diabetes since 3 yrs as her parents also have diabetes, and she's taking sugarfree gold sugar substitute 2-4 pellets everyday while having tea or milk, is sugar free safe?
Or will she has to continue insulin as her FAsting SUGAR count is 130 and PP is 175.
Last time when we had the first baby after 3 months of conceiv here apolo doctor suggested for insulin, but it's a painful procedure, can it be avoidable with glycomet 500 mg or even more dose.Pls advise.
doctor
Answered by Dr. Dr. Abhay A Mali (1 hour later)
Brief Answer:
Metformin can be continued with close monitoring of blood sugar levels.

Detailed Answer:
Hi,

Thanks for your question.
Noted your concern.

There are different types of artificial sweeteners many of them can be used in pregnancy in moderate amount.

Metformin can be continued in pregnancy depending upon blood sugar levels.
In pregnancy tight blood sugar control is required to avoid complications in both mother and baby.

Considering her fasting and post-prandial blood sugar levels there may be need for increasing the dose of Metformin with close monitoring of blood sugar levels.
Recommended blood sugar levels in pregnancy are premeal, bedtime, and
overnight blood glucose 60–99 mg/dl, peak postprandial glucose 100–129 mg/dl, and HbA1C 6.0.
Though these targets need to be individualized in each patient depending upon current blood sugar levels, medications and hypoglycemia risk.

If even with increasing the dose of metformin blood sugar levels are not within target range then insulin is the only option. Insulin gives rapid and reliable blood sugar control.

I may suggest to consult near by diabetologist or endocrinologist as physical examination, one to one counselling and with frequent follow ups are important.

Hope this helps.

Regards,
Dr. Abhay Mali.
Diabetologist.
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Dr. Abhay A Mali (10 hours later)
Thank you very much sir, here HBA1C is 6.4.
Thus is it required now to continue with Insulin or we can increase glycomet 500 to 1000 mg.
doctor
Answered by Dr. Dr. Abhay A Mali (3 hours later)
Brief Answer:
May suggest to increase dose of Metformin with blood sugar monitoring.

Detailed Answer:
HbA1c of 6.4 denote good blood sugar control.
I may suggest to increase dose of metfromin to 1500mg per day in divided doses over a period of 7 to 10 days.
With monitoring blood sugar level with glucometer at home.
I may suggest to monitor-
- Fasting
- 2 hours after breakfast.
- 2 hours after Lunch.
- 2 hours after dinner.
May suggest to give trial of increased dose of metformin for a period of 2 to 3 weeks.
If blood sugar levels are not within limits Insulin should be considered.

Obviously Final decision should be taken by her treating diabetologist.

Hope this helps.
Note: For further follow-up, discuss your blood glucose reports with our diabetologist. Click here.

Above answer was peer-reviewed by : Dr. Veerisetty Shyamkumar
doctor
Answered by
Dr.
Dr. Dr. Abhay A Mali

Diabetologist

Practicing since :2006

Answered : 807 Questions

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Can One Continue Metformin During Pregnancy?

Brief Answer: Metformin can be continued with close monitoring of blood sugar levels. Detailed Answer: Hi, Thanks for your question. Noted your concern. There are different types of artificial sweeteners many of them can be used in pregnancy in moderate amount. Metformin can be continued in pregnancy depending upon blood sugar levels. In pregnancy tight blood sugar control is required to avoid complications in both mother and baby. Considering her fasting and post-prandial blood sugar levels there may be need for increasing the dose of Metformin with close monitoring of blood sugar levels. Recommended blood sugar levels in pregnancy are premeal, bedtime, and overnight blood glucose 60–99 mg/dl, peak postprandial glucose 100–129 mg/dl, and HbA1C 6.0. Though these targets need to be individualized in each patient depending upon current blood sugar levels, medications and hypoglycemia risk. If even with increasing the dose of metformin blood sugar levels are not within target range then insulin is the only option. Insulin gives rapid and reliable blood sugar control. I may suggest to consult near by diabetologist or endocrinologist as physical examination, one to one counselling and with frequent follow ups are important. Hope this helps. Regards, Dr. Abhay Mali. Diabetologist.