Could Stilbesterol Taken Once During Pregnancy Lead To Breast Cancer To The Offspring 40 Years Later?

Posted on Mon, 25 Jun 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Mon, 25 Jun 2018 Answered on

Thu, 20 Jan 2022 Last reviewed on

Question : I have a question for a gynecologist/oncologist?

If a pregnant female was given 'Stilbesterol' in the first trimester of pregnancy 60 years ago to preserve the pregnancy, one dose only, could that cause that fetus (female) to develop breast cancer before age 40? The patient was well treated and is still a survivor today.

Answered by Dr. Dr. Rakhi Tayal (2 hours later)

Brief Answer:
Not likely.

Detailed Answer:

Hello,

A single dose of stilbesterol is not likely to cause such a change so as to predispose the baby to breast cancer. The effect would have been seen on the mother first. The effect of such medicines on the baby is much less as compared to its effect on the mother. A single dose is not likely to cause any such lasting damage.

I hope this answers your query.
In case you have additional questions or doubts, you can forward them to me, and I shall be glad to help you out.

Wishing you good health.
Regards.
Dr. Rakhi Tayal

Above answer was peer-reviewed by : Dr. Remy Koshy