Could Taking Fluconazole Intermittently Cause Birth Defects In The Fetus?

Posted on Sun, 10 Jun 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sun, 10 Jun 2018 Answered on

Thu, 22 Apr 2021 Last reviewed on

Question : I was starting my second week after conception when I TOOK FLUCONOZOLE 150 MG. TOOK IT EVERY 72HOURS FOR A TOTAL OF THREE TIMES. WHAT ARE THE CHANCES OF BIRTH DEFECTS? I HAVE READ HORRIBLE THINGS ON THE INTERNET. I AM VERY WORRIED THAT I could have hurt the baby.

Answered by Dr. Deepti Verma (18 minutes later)

Brief Answer:
Birth defects unlikely due to fluconazole

Detailed Answer:
Hi dear,
I have gone through your question and understand the concerns.
The high doses of fluconazole can lead to the birth defects in the fetus.
The doses should be as high as 400-800 mg taken altogether.
The dose of 150 mg taken at 72 hours interval is too low to pose any risk of congenital anomalies in the fetus.
I suggest you not to worry.
Hope you found the answer helpful.
Regards
Dr Deepti Verma
OBGYN
Maternal and fetal medicine specialist

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Above answer was peer-reviewed by : Dr. Prasad