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Diagnosed With MGUS. Taking Tbl 12. Looking For Suggestion

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Posted on Sat, 23 Feb 2013
Question: Hi I am XXXXXXX and I was diagnosed 2 years ago with MGUS though I don't have clinical details. My question is {since I am thinking of self medicating with TBL12} Why are people with a history of thyroid problems excluded from theTBL 12 trial?
Thank you
doctor
Answered by Dr. Indranil Ghosh (1 hour later)
Dear XXXXXXX

Thanks for writing in. In MGUS we usually do not recommend any treatment unless there is progression to myeloma. TBL-12 has shown some activity in myeloma but it is not clear whether it slows progression of MGUS to myeloma.

However, it is an extremely well tolerated product with rare side effects. I am not sure why they excluded patients with thyroid disorders. A currently ongoing study, which is not recruiting new patients, did not exclude such patients. You can access that study at WWW.WWWW.WW
Now it is really upto you whether you want to take it or not.

Hope I have answered your query. I will be available to answer further follow-up queries, if any.
Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Indranil Ghosh

Oncologist

Practicing since :2004

Answered : 1712 Questions

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Diagnosed With MGUS. Taking Tbl 12. Looking For Suggestion

Dear XXXXXXX

Thanks for writing in. In MGUS we usually do not recommend any treatment unless there is progression to myeloma. TBL-12 has shown some activity in myeloma but it is not clear whether it slows progression of MGUS to myeloma.

However, it is an extremely well tolerated product with rare side effects. I am not sure why they excluded patients with thyroid disorders. A currently ongoing study, which is not recruiting new patients, did not exclude such patients. You can access that study at WWW.WWWW.WW
Now it is really upto you whether you want to take it or not.

Hope I have answered your query. I will be available to answer further follow-up queries, if any.