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Diagnosed With Hepatitis C. HIV Test Came Indeterminate. Should I Be Worried?
Posted on
Fri, 25 Oct 2013
Medically reviewed by
Ask A Doctor - 24x7 Medical Review Team
Fri, 25 Oct 2013
Answered on
Mon, 11 Nov 2013
Last reviewed on
Question : if your hiv test results are p24 p51 p55 gp40 all these are present on the western blot test and it comes back indeterminate does that mean my body is in fected plus I was diagnosed with hepatitis c virus but they haven't gave me medication yet cause they want to see the viral load first whats your perspective on the hiv test could those anti bodies go away etc or coud my hepatitis c virus effect the test real scared ..
Brief Answer:
may or may not be, further investigation.
Detailed Answer:
Hello XXXX.
Thanks for your query at XXXXXXX
I understand your concern.
Positive HIV infection samples give many bands, indicating the presence of antibodies. Negative samples give no bands at all. Occasionally, incomplete patterns of bands corresponding to viral proteins are obtained (e.g., p24 alone, or p55 and p51 only, etc.). Such patterns constitute indeterminate results.
The causes include (1) tests done during seroconversion, (2) late-stage HIV infection, (3) cross-reacting nonspecific antibodies, (4) HIV vaccine recipients.
So indeterminate western blot does not indicate you have HIV infection nor it can rule out. Thats why it is called 'indeterminate'.
antibody reactivity.
Repeat testing by Western blot, ELISA, p24 antigen testing and clinical assessment, as well as consideration of other laboratory parameters (e.g., CD4 count) should be taken into account for further diagnosis and management of HIV infection.
Hope I answered your query.
Any further information you can ask me in follow up query .
Direct query at
WWW.WWWW.WW Regards.
may or may not be, further investigation.
Detailed Answer:
Hello XXXX.
Thanks for your query at XXXXXXX
I understand your concern.
Positive HIV infection samples give many bands, indicating the presence of antibodies. Negative samples give no bands at all. Occasionally, incomplete patterns of bands corresponding to viral proteins are obtained (e.g., p24 alone, or p55 and p51 only, etc.). Such patterns constitute indeterminate results.
The causes include (1) tests done during seroconversion, (2) late-stage HIV infection, (3) cross-reacting nonspecific antibodies, (4) HIV vaccine recipients.
So indeterminate western blot does not indicate you have HIV infection nor it can rule out. Thats why it is called 'indeterminate'.
antibody reactivity.
Repeat testing by Western blot, ELISA, p24 antigen testing and clinical assessment, as well as consideration of other laboratory parameters (e.g., CD4 count) should be taken into account for further diagnosis and management of HIV infection.
Hope I answered your query.
Any further information you can ask me in follow up query .
Direct query at
WWW.WWWW.WW Regards.
Above answer was peer-reviewed by :
Dr. Yogesh D
Answered by
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