Does Cyclobenzaprine Interact With Nortriptyline?

Posted on Thu, 31 Aug 2017

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Thu, 31 Aug 2017 Answered on

Sat, 16 Sep 2017 Last reviewed on

Question : I just took cyclobenzaprine 10 mg with nortriplyline 10 mg and found out they are contraindicated. What do I do?

Answered by Dr. Noble Zachariah (21 minutes later)

Brief Answer:
Discussion follows

Detailed Answer:
Hello,
Welcome and thanks for your query.
There are a few adverse interactions between the medicines and it is better to avoid taking them together. The main problem are cholinergic side effects like dryness of mouth, constipation or difficulty in urination. They can also cause sedation.
Rarely there can be symptoms of raised serotonin levels but unlikely at the doses of medicine you are on.
If you don't have any adverse effects now, don't worry but it would be a good idea to contact your doctor and discuss alternative medicines.

Take care

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar