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Does Cyclobenzaprine Interact With Zoloft?
Posted on
Sun, 23 Oct 2016
Medically reviewed by
Ask A Doctor - 24x7 Medical Review Team
Sun, 23 Oct 2016
Answered on
Mon, 14 Nov 2016
Last reviewed on
Question : Does Cyclobenzaprine conflict with zoloft?
Brief Answer:
Yes, it is not advisable to take both.
Detailed Answer:
Hello and welcome
Cyclobenzaprine and Zoloft together can have major, although rare, side effects. The problem with taking both is that they both can increase serotonin, and this can cause a serious and potentially life threatening "serotonin syndrome".
A safer choice with Zoloft, if you need something to relax your muscles, such as after an injury, would be a medication in the benzodiazepine family such as lorazepam or others.
I hope this information helps.
Yes, it is not advisable to take both.
Detailed Answer:
Hello and welcome
Cyclobenzaprine and Zoloft together can have major, although rare, side effects. The problem with taking both is that they both can increase serotonin, and this can cause a serious and potentially life threatening "serotonin syndrome".
A safer choice with Zoloft, if you need something to relax your muscles, such as after an injury, would be a medication in the benzodiazepine family such as lorazepam or others.
I hope this information helps.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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