Does Depakote Interact With Any Other Drug?

Posted on Wed, 27 Jan 2016

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Wed, 27 Jan 2016 Answered on

Mon, 14 Mar 2016 Last reviewed on

Question : My teenage granddaughter takes depakote ER 500 mg twice daily. She has a dry cough and I want to know if any cough medicine that should NOT be taken with her medications

Answered by Dr. Noble Zachariah (5 hours later)

Brief Answer:
Chlorpheniramine containing cough syrup

Detailed Answer:
Hello,

Welcome and thanks for your query.
Any cough syrup which contains Chlorpheniramine like Coldcough syrup can produce sedation, drowsiness , dizziness, confusion and difficulty in concentration when used with Depakote and is better avoided.
Take care,

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar