HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Does Depo Provera Shot Cause Deterioration Of Uterus Muscles?

default
Posted on Fri, 13 Feb 2015
Question: Hello Doctors -
My daughter had to have a hysterectomy at age 28 due to deterioration of uterus muscles (Muscle Atrophy). She was on the Depo Provera shot for about nine years. Is there any evidence that the Depo shot had anything to do with my daughter's problem. My email is YYYY@YYYY and my name is XXXXXXX Please help me understand what happened here. Thank you.
doctor
Answered by Dr. Dr. Soumen Patra (47 minutes later)
Brief Answer:
It could be uterine endometrial atrophy.

Detailed Answer:
Hello,

Thanks for writing to us.

Depo Shot has several adverse reactions if used for long term period. However, there is NO such evidence of uterine muscle atrophy.

It could be endometrial atrophy (uterine lining) due to overt use of Depo Shot as birth control and leads to irregular heavy menstrual bleeding (uncontrolled).

In that case, certain hysterectomy may need to perform for the benefit of patient and saving life in young age.

Hope, it helps for your information. Kindly, close the discussion if you don't have any other query.

Wish your good health and take care yourself.

Regards,
Dr S Patra

For future query, you can directly approach me through

http://doctor.healthcaremagic.com/Funnel?page=askDoctorDirectly&docId=63326
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
default
Follow up: Dr. Dr. Soumen Patra (3 days later)
Dr. Parra -

Please help me! Your answer, which appears to be an opinion you sent back to me in a few minutes, in not correct. There are numerous publication which prove you wrong. I did not pay for an opinion. I want the facts. Therefore, please provide me with the publication that supports your opinion or the publication of the correct harm the Depo Provera shot did to my daughter. Thank you, XXXXXXX Beegle from the University of Florida. I will look forward to your correct reply. Please do your research and provide me the correct facts.
doctor
Answered by Dr. Dr. Soumen Patra (8 hours later)
Brief Answer:
Details are given below.

Detailed Answer:
Hello,

Thanks for follow up query.

Uterine muscle atrophy is quite UNUSUAL or very much RARE event due to long term effect of Depo-Shot until there was congenital uterine anomaly.

Certain evidence shows that long term effect could be ATROPHIC endometrium or Vaginal atrophy or Chronic endometritis. These could be underlying pathology or fact.

For your reference, I give you the following links for detail study:

1) www XXXXXXX vcu.edu/home/resources/whh/IIdDepoProvera.pdf

2) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC0000/

3) http://www.hindawi.com/journals/criog/2013/835316/

Hope, it helps for you to understand properly.

Regards,
Dr S Patra
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
Dr.
Dr. Dr. Soumen Patra

OB & GYN Specialist

Practicing since :2011

Answered : 4059 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Does Depo Provera Shot Cause Deterioration Of Uterus Muscles?

Brief Answer: It could be uterine endometrial atrophy. Detailed Answer: Hello, Thanks for writing to us. Depo Shot has several adverse reactions if used for long term period. However, there is NO such evidence of uterine muscle atrophy. It could be endometrial atrophy (uterine lining) due to overt use of Depo Shot as birth control and leads to irregular heavy menstrual bleeding (uncontrolled). In that case, certain hysterectomy may need to perform for the benefit of patient and saving life in young age. Hope, it helps for your information. Kindly, close the discussion if you don't have any other query. Wish your good health and take care yourself. Regards, Dr S Patra For future query, you can directly approach me through http://doctor.healthcaremagic.com/Funnel?page=askDoctorDirectly&docId=63326