Does Gabapentin, Cyclobenzaprine, Diclofenac Sodium Or Acetaminophen Cause Kidney Failure?

Posted on Mon, 17 Sep 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Mon, 17 Sep 2018 Answered on

Thu, 21 Apr 2022 Last reviewed on

Question : DO ANY OTHESE DRUGS CAUSE KIDNEY FALIURE, GABAPENTIN,CYCLOBENZAPRINE,ACETAMINOPHEN, AND DICLOFENAC SODIUM

Answered by Dr. Dr. Prasad J (50 minutes later)

Brief Answer:
Diclofenac Sodium and Gabapentin

Detailed Answer:

Hi,

Amongst the medicines listed acetaminophen is metabolized by liver and it's completely safe on kidneys. The others are metabolized by kidney and therefore can cause damage on kidneys. That being said, diclofenac sodium as well as Gabapentin are known to cause acute renal injury and failure. Cyclobenzaprine is relatively safe on kidney and less likely known to cause failure.

Hope this answered your question. Let me know if you need clarifications.
Regards

Above answer was peer-reviewed by : Dr. Prasad