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Does Gabapentin Interact With Klonopin?

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Posted on Mon, 23 Oct 2017
Question: Is there an interaction with gabapentin and klonapin
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Answered by Dr. Ishu Bishnoi (1 hour later)
Brief Answer:
Interaction between gabapentin and Klonopin

Detailed Answer:
Hi Janbrown1942, thanks for asking from HCM.


I can understand your concern. These two drugs act on GABA mediated nerve conduction (inhibitory pathway).

As such, no interaction has ever been reported between Gabapentine and Klonopin (clonazepam) while taking simultaneously. But both these drugs cause sedation due to central nervous system inhibition. So while taking both drugs, consult your doctor for possible side effect of sedation, dizziness.

Avoid driving vehicle and do not do activities which require concentration.

Hope you got the point. If any doubt, do let me know.
Thanks. Take care.
Above answer was peer-reviewed by : Dr. Nagamani Ng
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Answered by
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Dr. Ishu Bishnoi

Neurologist, Surgical

Practicing since :2007

Answered : 901 Questions

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Does Gabapentin Interact With Klonopin?

Brief Answer: Interaction between gabapentin and Klonopin Detailed Answer: Hi Janbrown1942, thanks for asking from HCM. I can understand your concern. These two drugs act on GABA mediated nerve conduction (inhibitory pathway). As such, no interaction has ever been reported between Gabapentine and Klonopin (clonazepam) while taking simultaneously. But both these drugs cause sedation due to central nervous system inhibition. So while taking both drugs, consult your doctor for possible side effect of sedation, dizziness. Avoid driving vehicle and do not do activities which require concentration. Hope you got the point. If any doubt, do let me know. Thanks. Take care.