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Does Hydrocodone Interact With Prozac?
Question: I was prescribed hydrocodone for my back pain and forgot to find out if there are any drug interactions with Prozac. Thank you!
Brief Answer:
High doses should be avoided.
Detailed Answer:
Hello thanks for asking from HCM for your health related doubts
Hydrocodone is an opioid drug while Prozac is an antidepressant. Its safe to use both drugs together in prescribed dose. But Hydrocodone is known to raise the concentrations of Prozac and if both drugs are in high dose then there is some risk of serotonin syndrome. But that is seen in high doses. Hydrocodone reduces metabolism of Prozac. Otherwise there are no significant drug interactions at clinically used doses.
Thanks and Take care.
You are welcome to ask follow up doubts.
High doses should be avoided.
Detailed Answer:
Hello thanks for asking from HCM for your health related doubts
Hydrocodone is an opioid drug while Prozac is an antidepressant. Its safe to use both drugs together in prescribed dose. But Hydrocodone is known to raise the concentrations of Prozac and if both drugs are in high dose then there is some risk of serotonin syndrome. But that is seen in high doses. Hydrocodone reduces metabolism of Prozac. Otherwise there are no significant drug interactions at clinically used doses.
Thanks and Take care.
You are welcome to ask follow up doubts.
Note: For further guidance on mental health, Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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