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Does Mucinex Interact With Donepezil?

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Posted on Thu, 21 Jul 2016
Twitter Thu, 21 Jul 2016 Answered on
Twitter Wed, 10 Aug 2016 Last reviewed on
Question : My husband has early on set ALZ and has a cough so is it okay to give him Mucinex or anything else for congestion? He takes Donepezil.
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Answered by Dr. Olsi Taka (30 minutes later)
Brief Answer:
It is okay

Detailed Answer:
I read your question carefully and I understand your concern.

I think that you can safely try Mucinex. It does not have any interaction with Donepezil.

It can cause some sedation in some patients but a mild one shouldn't be a problem.

It doesn't affect Alzheimer's in any negative way either, actually may even have some benefit as it is thought it may antagonize NMDA receptors like another class of ALZ drug, memantine (not that it is approved to treat ALZ or that I am suggesting it should be used for that purpose, mind you).

I remain at your disposal for other questions.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Olsi Taka

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Practicing since :2004

Answered : 3670 Questions

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Does Mucinex Interact With Donepezil?

Brief Answer: It is okay Detailed Answer: I read your question carefully and I understand your concern. I think that you can safely try Mucinex. It does not have any interaction with Donepezil. It can cause some sedation in some patients but a mild one shouldn't be a problem. It doesn't affect Alzheimer's in any negative way either, actually may even have some benefit as it is thought it may antagonize NMDA receptors like another class of ALZ drug, memantine (not that it is approved to treat ALZ or that I am suggesting it should be used for that purpose, mind you). I remain at your disposal for other questions.