Does Nystatin Allergy Cause Skin Rash?

Posted on Wed, 26 Mar 2014

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Wed, 26 Mar 2014 Answered on

Tue, 22 Apr 2014 Last reviewed on

Question : Hello, my granddaughter was brought into her Pediatricians office for thrush. She was prescribed Nystatin cream for her bottom. it was applied twice and now she has an even worse rash along with blisters on her bottom. Could she be allergic to the Nystatin?

Answered by Dr. Eric Goldstein (25 minutes later)

Brief Answer: Nystatin Detailed Answer: Hello. Thank you for your question. Although anything can happen, allergy to Nystatin is very unusual. I think it is more likely that in addition to the fungus that caused the rash, there is also some bacteria involved. as the Nystatin begins to eradicate the fungal component, the bacterial component worsens the rash. I don't have the benefit of being able to view the rash with my own eyes. However, I believe and over-the-counter antibiotic ointment, such as Bacitracin, apllied three times per day, will be beneficial. If the rash continues to worsen over the next 2-3 days, I recommend consulting with your doctor.

Above answer was peer-reviewed by : Dr. Yogesh D