Does Remeron Effect Gabba Receptors?

Posted on Sat, 31 Mar 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sat, 31 Mar 2018 Answered on

Tue, 30 Apr 2019 Last reviewed on

Question : Does the medicine Rameron effect the same gabba receptors as benzo diazepam does? From what Im led to believe it doesn't

Answered by Dr. Ashok Kumar Choudhary (55 minutes later)

Brief Answer:

No, it does not

Detailed Answer:

Hello,

Although both Remeron (Mirtazepine) and benzodiazepines are helpful for sleep problems there is no resemblance at the receptor level between these two medications.

The benzodiazepines act on the gaba receptors while the Mirtazapine increases the serotonergic and noradrenergic transmission.

In addition, mirtazapine also blocks histamine receptors which are often responsible for sedation as a side effect. Sometimes this effect on histaminergic receptors is used for individuals with a sleep problem.

I also like to inform you that action on gaba results intolerance after a certain period of time but no such effect observed for receptors acted upon by Remeron.

Hope I have answered your query.

Take care

Regards,
Dr Ashok Kumar, Psychiatrist

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar