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Does High Dose Of Lisinopril Stop Functioning Of Heart?

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Posted on Thu, 15 May 2014
Question: stopping your heart

Is it possible to take enough Lisinopril to stop your heart?
doctor
Answered by Dr. Dr.Albana Sejdini (1 hour later)
Brief Answer:
Not known until now...

Detailed Answer:
Hi there,

Lisinopril is an anti-hypertensive drug which can decrease high blood pressure. In rare cases, if taken in higher dosage than normal, can cause hypotension. If this occurs, heart starts pumping more frequently to get blood pressure back to normal again.

In other words, our body has its own mechanisms and is prepared to bring low blood pressure back to normal again. Unless, this mechanisms are broken and fail to do so.

Until now, no study has suggested that Lisinopril can stop your heart.

All the best!
Dr.Albana
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr.Albana Sejdini (45 hours later)
So you are saying that it is not possible to stop your heart with taking several, several Lisinopril. That our bodies will protect us from an overdose?
doctor
Answered by Dr. Dr.Albana Sejdini (3 hours later)
Brief Answer:
Following answers to your queries....

Detailed Answer:
Hi back,

Thank you for following up.

If given in therapeutic dose, lisinopril cannot cause you harm. However, frequent monitoring (every 6 months) of heart, liver and kidney levels are recommended to prevent undesirable side effects.

Unless, severe allergic reactions can be occur. That's why, I always advise my patients to look for signs of allergic reaction when taking lisinopril or other drugs even if they might have been taking it for longer time. An allergic reaction can occur anytime.

In cases of overdose, there are many other data to be considered:
- who took the overdose accidentally : children? elder? (age)
- what other health problems the person has : preexisting congestive heart failure, renal disease, hypovolemia?

Even in cases where extra dose has been taken, there is no evidence to show that people died due to that extra dose, including children. Most of them have remained asymptomatic; while others showing signs of hypotension and electrolyte imbalance.

When it comes to electrolytes, potassium is accumulated inside the bloodstream (hyperkalemia) while sodium is excreted (hyponatremia) through kidneys. So, if any heart problem would occur, it would be related to hyperkalemia, especially in patients with preexisting pathologies as mentioned above.

Hope it answered to your question at your satisfaction! Let me know if you need further clarifications. If not, kindly rate this answer while closing it.
Thank you!
Dr.Albana
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Dr.Albana Sejdini

General & Family Physician

Practicing since :2006

Answered : 7303 Questions

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Does High Dose Of Lisinopril Stop Functioning Of Heart?

Brief Answer: Not known until now... Detailed Answer: Hi there, Lisinopril is an anti-hypertensive drug which can decrease high blood pressure. In rare cases, if taken in higher dosage than normal, can cause hypotension. If this occurs, heart starts pumping more frequently to get blood pressure back to normal again. In other words, our body has its own mechanisms and is prepared to bring low blood pressure back to normal again. Unless, this mechanisms are broken and fail to do so. Until now, no study has suggested that Lisinopril can stop your heart. All the best! Dr.Albana