Brief Answer:
HIV testing
Detailed Answer:
Hi.
Thanks for the additional information. HIV Combo test reduces the window period of detection of HIV to 28 days/4 weeks i.e if the person is negative by this test after 4 weeks of last sexual contact then it can be concluded fairly accurately, that the person is HIV negative. In your friend's case however, the girl in question was tested but what about her sexual contacts, if any, over the past 4 weeks before testing? If she did'nt had any sexual contacts in the preceding 4 weeks before this test, then she is clean and your friend is probably clean as well. However if she has had sexual encounters in the preceding 4 weeks then you cannot rely on this particular test report, inspite of being negative.
HIV Combo test/
DUO test is also known as the 28 day HIV test. This test can detect the virus from 28 days after infection and is called a "Duo" test OR "Combo" test because it combines an antibody test for HIV type 1 & 2 strains of the virus along with an antigen test for the P 24 antigen. So the HIV DUO test can detect an infection before the antibody test can, it is used for diagnosing HIV much earlier in the course of infection. The test, is considered 99.8% accurate at 28 days, this accuracy increases to 99.9% at 90 days after any potential contact.
Thus, if the Antigen test is negative after 28 days or 4 weeks of the last sexual contact, then it almost certainly rules out HIV. However, even then a negative result needs to be confirmed with a second test after 90 days, if the exposure is less than 3 months ago.
Therefore, if the girl in question has had sexual contacts with others over the past 28 days OR 4 weeks, she might test negative but she can still transmit the virus if she was contracted HIV from someone, in the preceding 4 weeks, because she will still be in the window period of detection by HIV Combo test.
regards