Good Morning (my Time): I Came Across A Product That

Posted on Sun, 13 Jan 2019

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sun, 13 Jan 2019 Answered on

Last reviewed on

Question : Good morning (my time):
I came across a product that is said to slow atherosclerosis progression as written up in the Lancet Magazine. It is called Pycnogenol. A human controlled trial showed that this substance was able to improve endothelial function in patients with CAD, an effect that helps limit the progression of atherosclerosis. Have you heard of it please?

Answered by Dr. Bhanu Partap (-4 hours later)

Brief Answer:
Please refer to the detailed answer below

Detailed Answer:
Hello

It’s basically a herbal extract from pine which has come clinical studies or trials been conducted for ADHD attention deficit hyperactivity disorder.

For CAD there has not been any conclusive studies or data being published. Neither have we ever used nor much heard about it being practiced in cardiology.

It’s advisable not to use any such product without medical advice or supervision.

I hope this information will guide you properly.

Kind Regards
Dr Bhanu Partap

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Bhanu Partap (2 hours later)

Disagree...I sent you the link which has the medical studies....

Follow up: Dr. Bhanu Partap (1 hour later)

Hi Dr. Bartap ~ below is the link with the studies I discussed. Please take the time to check this out, and get back to me.
https://www.lifeextension.com/magazine/2016/2/slow-the-progression-of-atherosclerotic-plaque/page-01?p=1

I do not have CAD ...I have PAD and NIC...
THank you,
m. reilley, MA, tEFL

Follow up: Dr. Bhanu Partap (21 minutes later)

Here are some good references based on medical studies:

https://journals.lww.com/cardiovascularpharm/Fulltext/1998/10000/Endothelium_Dependent_Vascular_Effects_of.1.aspx

Follow up: Dr. Bhanu Partap (3 minutes later)

And some more =

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC0000/

Cheers!

Answered by Dr. Bhanu Partap (11 hours later)

Brief Answer:
Hello again

Detailed Answer:
Thanks for the reference, appreciate that.

These studies which you are giving references of are of animal models (rats).

As I said earlier I have not come across any conclusive evidence based results for humans.

With Regards
Dr Bhanu Partap

Above answer was peer-reviewed by : Dr. Vaishalee Punj

Follow up: Dr. Bhanu Partap (8 hours later)

Here you go Sir...
https://bmcclinpharma.biomedcentral.com/articles/10.1186/1472-6904-6-4

https://nutritionj.biomedcentral.com/articles/10.1186/1475-2891-11-11

https://www.sciencedirect.com/science/article/pii/S0000

https://genesandnutrition.biomedcentral.com/articles/10.1007/s12263-009-0135-4

Cheers!

Answered by Dr. Bhanu Partap (55 minutes later)

Brief Answer:
Hello again

Detailed Answer:
Looks like you have done some extensive research on this.

Thanks for updating me on this. As you have asked me that Have I heard of it.

But we are not using this as of now.

If you are not be satisfied with the answer, so with all due respect sir you can go for your refund.

With Regards
Dr Bhanu Partap

CHEERS !!!

Above answer was peer-reviewed by : Dr. Prasad