Had A Positive Effect With Wellbutrin. Is It Safe To Increase The Dosage?

Posted on Sat, 9 Nov 2013

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sat, 9 Nov 2013 Answered on

Sat, 30 Nov 2013 Last reviewed on

Question : I just started with 150 mg of Wellbutrin 2 days ago and had a positive effect within 24 hours but it seems to have gone away. Is this normal? Is it safe to go ahead and double the dosage?

Answered by Dr. Shoaib Khan (45 minutes later)

Brief Answer: Yes, can be normal; please do not increase dose Detailed Answer: Hello sir and welcome. Thank you for writing to us, Yes sir, 150 mg of wellbutrin can have an effect lasting from about 2-4 days, varying from person to person, so this would be considered normal. Also in your case, as you have just started on the medication it may take sometime till the effect of the medication becomes constant, so please be patient. As for doubling the dosage, this would not be considered safe unless your prescribing doctor thinks it necessary, and would take the utmost care in ensuring your safety, as overdoses can result in seizures. In my opinion, you can wait for a few days sir (3-5 days), and if the effect of the medication does not become constant, then please contact your doctor and see if he can either increase the dosage or substitute it with another medication. I hope you find my response helpful sir. Please feel free to write back to me for any further clarifications, I would be more than happy to help you. Wishing you nothing but good health. God bless.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar