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Have Fibromyalgia. Taking Amytriptolene, Cymbalta. Having Trouble In Sleeping. What To Do?

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Posted on Sat, 23 Mar 2013
Twitter Sat, 23 Mar 2013 Answered on
Twitter Sat, 20 Apr 2013 Last reviewed on
Question : Hi I'm XXXXXXX Ive had fibromyalgia for 30 yrs. Amytriptolene 5 tablets of 50mg taken each night worked the best. Over the last mo. I am on cymbalta 60mg to see if I can lose weight. I.m having trouble sleeping so I started taking the cymbalta in the a.m. 2 weeks ago...but I still can't sleep.. Could I try 2 50mg amytriptolene at night and cymbalta in the a.m. I plan on seeing my Dr. this week. Also the pain is with me again. I'm in tears. Thankyou
doctor
Answered by Dr. Sree Gouri SR (2 hours later)
Hi,
Thanks for the query.

Amytriptolene is a tricyclic antidepressant and it belongs to selective seratonin re-uptake inhibitors.
Cymbalta contains duloxetine and it belongs to seratonin-norepinephrine re-uptake inhibitors.
Usually these drugs can act individually for fibromyalgia.
But usage of cymbalta for weight reduction is not specified.
If both the drugs are used that can lead to a condition called serotonin syndrome, that can lead to many side effects.
So you better stop cymbalta till you approach your doctor and continue the same dosage of amytriptolene. Possibly this can help.
Hope I have answered your query. I will be available to answer your follow up queries. If you are satisfied with all my answer, please rate the answer after closing the discussion.
Take care.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sree Gouri SR (10 hours later)
Thankyou, I will seee my Dr. this week.
doctor
Answered by Dr. Sree Gouri SR (34 hours later)
Hi,
Ok, wish you good health.
Wish you Good Health, If you are satisfied with my response please rate the answer after closing the discussion.
Take care.
Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Sree Gouri SR

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Have Fibromyalgia. Taking Amytriptolene, Cymbalta. Having Trouble In Sleeping. What To Do?

Hi,
Thanks for the query.

Amytriptolene is a tricyclic antidepressant and it belongs to selective seratonin re-uptake inhibitors.
Cymbalta contains duloxetine and it belongs to seratonin-norepinephrine re-uptake inhibitors.
Usually these drugs can act individually for fibromyalgia.
But usage of cymbalta for weight reduction is not specified.
If both the drugs are used that can lead to a condition called serotonin syndrome, that can lead to many side effects.
So you better stop cymbalta till you approach your doctor and continue the same dosage of amytriptolene. Possibly this can help.
Hope I have answered your query. I will be available to answer your follow up queries. If you are satisfied with all my answer, please rate the answer after closing the discussion.
Take care.