Have Had A TURP Done. Having Pain And Burning Sensation In Penis. What Is The Dose Of Imipenam?

Posted on Wed, 17 Oct 2012

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Wed, 17 Oct 2012 Answered on

Wed, 7 Nov 2012 Last reviewed on

Question : dare Sir,I have had a TURP done12 days ago.I was discharged 8 days ago.Eversince coming back from the hospital I have been having terrible burning feeling in the urethan coupling of pain I was given Amikacin injection which did not give relief.Subsequently I did urine culture which showed>0000 colonies/ml significant bacteriuria and isolation1 enterbacter cloacae*0000 1 CHB it was resistant all antibiotics except PENEM IMPIPENEM.KINDLY LET ME KNOW WHAT IS THE DOSSAGE and how long.The pain is killing
I do not have fever.I am always XXXXXXX pain and burning sensation in pennies.How long will take to control this infection and what dosage

Answered by Dr. G.Srinivasan (9 hours later)

Hi sir,

Welcome to XXXXXXX Sorry to hear about your suffering.
The dose of imipenam/cilastatin is 1-2 g daily in divided doses every 6-8 hr, given via IV infusion. Doses 250 or 500 mg are infused over 20-30 min, and doses of 750 mg or 1 g over 40-60 min. Max: 4 g/day or 50 mg/kg body weight.
Duration is 3 to 7 days.

In addition
1. Urinary analgesics like PYRIDIUM,
2. Urinary anti-spasmodics like FLAVOXATE,
3. Plenty of oral fluids,
4. Avoiding spicy diet
should help.

After 3 days of injection, it is better to recheck urine culture for response---

Get well soon.
Regards
DR GS

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar