Have Hypothyroidism. Reports Show High Gamma GT Levels And T4 Levels. What Should I Do?

Posted on Thu, 12 Dec 2013

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Fri, 13 Dec 2013 Answered on

Thu, 2 Jan 2014 Last reviewed on

Question : Hi. I have high gamma GT levels-212 in Oct; 155 in May this year, but drink very little alcohol. I have hyperthyroidism and have been taking amytryptiline for 3years now for peripheral neuropathy(adverse reaction to swine flu vaccine).i have now been told that my T4 levels are too high! Any idea what is going on? I am 52,perimenopausal.Thanks

Answered by Dr. Dr. Ivan Romich (8 hours later)

Brief Answer: Hi and welcome to XXXXXXX Detailed Answer: Thanks for the query. GGT is used mainly for detecting liver diseases including excessive alcohol intake,but it may indicate any other liver disease,hepatitis,gallbladder issue as well as cardiovascular diseases. Also some drugs can cause liver enzymes elevation(including amytriptiline). If your other LFTs are fine and you odnt have any liver related symptoms, then isolated GGt elevation isnt worrying and you should just avoid alcohol and fatty food in next 3-4 weeks and repeat blood test then. You should do just liver ultrasound to rule out some morphologic liver changes. Your hypthyroidims problem probably isnt related to ggt levels. It is not uncommon that hypo- becomes hyperthyroidms or conversely. There can be thyroid tissue that became hyperfunctional. usually this is just thyroid hyperplasia or adenoma,but sometimes it can be something more serious such as tumors. So I would sugest to do thyroid ultrasound or scintigraphy to see the exact cause of high T4 and determine is medical therapy necessary. Wish you good health. Feel free to ask. Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar