Question: my friend has been experiencing problems since october with severe fatigue, difficulty concentrating(this is worsening), some difficulty with joint pain bilaterally in wrist and ankles and fatigue. Some numbness and burning in toes. Difficulty at first with lifting arms and legs but this has improved and has moved to fatigue. She smells smoke when there isn't any. She has been seen by a neurologist(october) a rheumatologist(just last week) and has had a negative, XXXXXXX thyroid, cbc, metabolic pain, rheumatoid factor, and now her MRI says there is some t2 prolongation with in subcortical white matter in L frontal lobe and mild prominence of a draining vein along the anterior aspect of the R temporal lobe but no other abnormalities. She is not a "stressed" out person, she does Tai Chi daily, she eats right and is not overweight. Do you have any suggestions or thoughts? She also feels like it is difficult to take a deep breath and feels short of breath. She has been checked for a hernia which was negative and chest xrays and hand xrays are normal