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Hello - I Know That You Are Endorinalogist - And

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Posted on Mon, 1 Aug 2022
Question: Hello - i know that you are endorinalogist - and you gone understand this article


i have question about your article
The treatment outcomes were further classified as successful (cured and completed treatment), or unsuccessful (died, failed treatment, loss to follow up, changed diagnosis, ongoing treatment and treatment interrupted).


In multivariable analysis, a TB patient with DM has 3.5 higher odds to develop unsuccessful treatment outcome compared to TB patients without DM


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC0000/#!po=45.3125

I studied it - about diabetes and TB treatment outcome - if i look on table 4

I did not find any huge difference less number with Diabetes completed treatment, and failed treatment more diabetes group

But looking one other numbers - diabetes had fewer %

If in article said


In multivariable analysis, a TB patient with DM has 3.5 higher odds to develop unsuccessful treatment outcome compared to TB patients without DM

How can you get such mummer difference that DM have less successful treatment outcome ? -

i can not understand

Please can you give me small comment

Thank you very much
doctor
Answered by Dr. Dr.Raju.A.T (15 hours later)
Brief Answer:
Blood sugar controll

Detailed Answer:
Hi,

Thanks for your query.

Its not just being diabetic matters here. Its the blood sugar control. Patients with good glycemic control can have successful treatment and ones which poor control can end up with unsuccessful treatment or relapse in the future.

The treatment course remains the same in diabetic and non diabetic. Its the glycemia which determines the outcome.

If in long-term diabetic which micro/ macrovascular complications already set in, the success of TB treatment matters on which end-organ damage is established. The clearance of medications, contraindications, toxicities etc an be one of the causes of treatment failure if the organs involved are damaged due to diabetes no matter the glycemic control.

Hope, I answered your query.

Please do ask if any doubts

Regards,
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Dr.Raju.A.T

General & Family Physician

Practicing since :2008

Answered : 4932 Questions

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Hello - I Know That You Are Endorinalogist - And

Brief Answer: Blood sugar controll Detailed Answer: Hi, Thanks for your query. Its not just being diabetic matters here. Its the blood sugar control. Patients with good glycemic control can have successful treatment and ones which poor control can end up with unsuccessful treatment or relapse in the future. The treatment course remains the same in diabetic and non diabetic. Its the glycemia which determines the outcome. If in long-term diabetic which micro/ macrovascular complications already set in, the success of TB treatment matters on which end-organ damage is established. The clearance of medications, contraindications, toxicities etc an be one of the causes of treatment failure if the organs involved are damaged due to diabetes no matter the glycemic control. Hope, I answered your query. Please do ask if any doubts Regards,