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Hello I Have Question About B Hepatitis In One Article

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Posted on Thu, 23 Jun 2022
Question: Hello i have question about B hepatitis

in one article it is said that B hepatitis cause of death was - Among the 540 deaths with hepatitis B as underlying cause, 127 (23.52%) were due to acute infection and 413 (76.48%) due to chronic infection
https://scielosp.org/article/rsp/2020.v54/124/


But in other article it is said

(0.4%) was seen for acute hepatitis B (18 deaths
among 4257 cases)

https://sci-hub.se/10.1016/s1590-8658(03)00157-9

Most people chronically infected with hepatitis B can
expect to live long and healthy lives. Individuals with
chronic HBV may not develop symptoms for up to 30
years.

https://www.ndhealth.gov/disease/hepatitis/Docs/NowWhat/ImPositiveNowWhat_FactSheet_HBV.pdf

So in conclusion if Acute B hepatitis have mortality rate 0.4 % - and i cause 23 % of all death -
it means that most case also chronic B hepatitis will live normal long life as 15 % could develop cirrhosis 30 - 50 years

Most of chronic B hepatitis will manage to live long life !

Thank you very much
doctor
Answered by Dr. Elona (2 days later)
Brief Answer:
True

Detailed Answer:
Hello
I have gone through your query.
I can understand your concern.

It is true that most of patients with chronic B hepatitis live long, healthy and full lives.althought they have an increased risk of developing liver disease9especial cirrhosis) later in life.

My advice for you is to consult a liver specialist every six months, or more often as needed because it is necessary t take some specific medication called antiviral medication that can help fight the virus and slow its ability to damage your liver.

Hope i have clarified all our doubts.

Wish you all the best.


Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Elona (2 hours later)
Hello !

I understand that you ar not infectalogist - but you understand basics

I work in hematology laboratory - i have HBV vaccine and do blood test every year

there is termin like occult HBV - like HBV test negative - but HBV DNA positive

I called to one doctor infectalogist and she staid that there is no need for occult HBV screening in healthy HCW

So as she said it should be like that

So i understand thous who have lover immunity do to some disease, and ar going for immunsuresive therapy need screen for occult HBV - others Healthy HCW ( health care workers ) persons should not


is is said thous who have some contact with HBV could have it low level in liver and in blood - even if they are vaccinated

Recent studies showed that immune response to
HBV remains vigorous long after an acute infection. In addition, HBV DNA can be detected by polymerase chain reaction
(PCR) assays in serum, liver, and peripheral blood mononuclear cells more than a decade after an apparent recovery from
HBV infection.4-6 These findings suggest that recovery from
acute hepatitis B may not result in complete virus elimination,
but rather the immune system keeps the virus at very low
levels. There is, however, no clear evidence that patients who
have persistently low levels of HBV after recovery from acute
hepatitis B develop progressive liver disease

https://deepblue.lib.umich.edu/bitstream/handle/2027.42/34784/0000_ftp.pdf;sequence=1


Health care workers are more often at high risk of HBV infection/OBI than the general population[185,186]. They may contract HBV transmission via exposure to potentially infected material as well as mucosal-cutaneous and percutaneous exposure to HBV from HBV carriers

There is one article that HCW sould screen for occult HBV

But as infectalogist doctor said there is no need for occult HBV screening in healthy HCW

Health care workers are more often at high risk of HBV infection/OBI than the general population[185,186]. They may contract HBV transmission via exposure to potentially infected material as well as mucosal-cutaneous and percutaneous exposure to HBV from HBV carriers

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC0000/#__ffn_sectitle

Thank you


Answered by
Dr.
Dr. Elona

Endocrinologist

Practicing since :2008

Answered : 942 Questions

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Hello I Have Question About B Hepatitis In One Article

Brief Answer: True Detailed Answer: Hello I have gone through your query. I can understand your concern. It is true that most of patients with chronic B hepatitis live long, healthy and full lives.althought they have an increased risk of developing liver disease9especial cirrhosis) later in life. My advice for you is to consult a liver specialist every six months, or more often as needed because it is necessary t take some specific medication called antiviral medication that can help fight the virus and slow its ability to damage your liver. Hope i have clarified all our doubts. Wish you all the best.