How Does Free Beta Hcg Level Convert To MOM?

Posted on Wed, 5 Jun 2013

Question: hi - my free beta HCG level for 13 weeks was 162.57 ng/m - how does that convert to MOM?

Answered by Dr. Aarti Abraham (2 hours later)

Hello XXXXXXX
Thanks for your query.

The hCG hormone is measured in milli-international units per milliliter (mIU/ml).
Normally, hCG levels in weeks from LMP (gestational age) are as follows :

3 weeks LMP: 5 – 50 mIU/ml
4 weeks LMP: 5 – 426 mIU/ml
5 weeks LMP: 18 – 7,340 mIU/ml
6 weeks LMP: 1,080 – 56,500 mIU/ml
7 – 8 weeks LMP: 7, 650 – 229,000 mIU/ml
9 – 12 weeks LMP: 25,700 – 288,000 mIU/ml
13 – 16 weeks LMP: 13,300 – 254,000 mIU/ml
17 – 24 weeks LMP: 4,060 – 165,400 mIU/ml
25 – 40 weeks LMP: 3,640 – 117,000 mIU/ml
Non-pregnant females: <5.0 mIU/ml
Postmenopausal females: <9.5 mIU/mlAs

As serum marker levels change with gestational age, there is no single value to use as a reference for high or low measurement. Instead, serum marker results are reported as a multiple of the median (MoM).

A MoM value of 1 means that the marker level is equal to the median level for an unaffected pregnancy with the specified gestational age, maternal weight, ethnicity and smoking status.

A MoM value of 2 means that the marker level is twice as high as the median level for an unaffected pregnancy with the specified gestational age, maternal weight, ethnicity and smoking status.

You need to provide more details for me to be able to assist you.
Looking forward to hearing from you
Take care.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Aarti Abraham (23 hours later)

Hi - thanks. I'm not sure what other info you could need. Below is my full report. You'll notice that they put my GA as 12 weeks 4 days, but that was wrong (which they confirmed was wrong yesterday). My GA was 13 weeks 0 days. I didn't want them to run the report again because I think it will mean worse results. I did take the harmony test last week and am in agony as I wait. I'm just finding it very hard not to be super anxious.

Tests: (1) First Trimester Screen FB (FIRSTTRIFB)
! RISK TABLE -
! Down Syndrome [A] Increased Risk
1st Trimester cutoff: 1 in 307
Risk Before Screening: 1 in 207
Risk After Screening: 1 in 295
! Trisomy 18/13 Within Range
1st Trimester cutoff: 1 in 150
Risk Before Screening: 1 in 377
Risk After Screening: 1 in 7,521
! COMMENTS -
Nasal bone results are used only for the Down syndrome risk calculation but not for Trisomy 18/13 Blood draw for MSAFP for open neural tube defects, or other second trimester screening must be collected between 5/20/2013 and 7/7/2013 Recommendations for Follow-up: Genetic counseling and offer CVS or amniocentesis
! MARKERS/ANALYTES -
! Free Beta hCG -
Value: 162.57 ng/ml
MoM: 3.32
Percentile: 99.0
! PAPP-A -
Value: 1.43 mlU/mL
MoM: 1.15
Percentile: 50.0
! NT -
Value: 2.0 mm
Delta: 0.39
Percentile: 75.0
! Nasal Bone Present
! Demographics -
Sonographer: XXXXXXX FINCH
Age at EDC: 36
Maternal Weight: 172
Ethnicity: Caucasian
Previous Child Hx: None
Multiple Pregnancy: No
Ultrasound Date: 05/03/2013
GA at Ultrasound: 12w4d
Draw Date: 05/03/2013
GA at Draw: 12w4d (CRL)
Date Received: 05/04/2013
CRL (mm): 63.8
Report Date: 05/06/2013
! Footer -

Answered by Dr. Aarti Abraham (25 minutes later)

Based on the results of your serum markers, you appear to have increased risk of Downs syndrome in the current pregnancy.
This is just a screening test, and this tells you that you have increased risk of Downs syndrome compared to the general population, and not that your child WILL have downs syndrome.
Confirmatory for ruling out Downs syndrome would be amniocentesis, wherein the cells of the baby would be examined for this chromosomal anomaly.
You would be offered the option of going in for this test, based on the results.
Take care.

Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar