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How Effective Is Temodal Chemotherapy For Adenoid Cystic Carcinoma?

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Posted on Wed, 11 Apr 2012
Question: Dear doctor,
My wife suffers of adenoid cystic carcinoma with metastases on lungs and liver (tumor on liver grows relatively fast ~0.5 cm per month).
I am interested to know ability to treat by temodal and about the efficiency of this treatment.
Thank you,
Eli
doctor
Answered by Dr. Puneet Maheshwari (56 minutes later)
Hi,

Thanks for the query,

I have gone through the history, Adenoid cystic carcinoma is a malignant tumor, that metastasizes.

Let me tell you about the TEMODAL chemotherapy.

#Temodal capsule contains temozolomide.

#TEMODAL Capsules are indicated in treatment of patients with reccurent malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma, or any fast growing malignant tumor.

#Therapy can be continued until disease progression stops.

#Temodal should be administered in the fasting state. Antiemetic therapy may be administered prior to or following administration of Temodal.

If vomiting occurs after the dose is administered a second dose should not be administered that day.

EFFICACY OF TEMODAL---

#Use of TEMODAL in combination with other alkylating agents may increase the likelihood of myelosuppression.

#Clinical data suggests it prolongs the progression-free period and overall survival.

#Temozolomide prevents the growth of cancer cells by interfering with the genetic material (DNA) that is necessary for reproduction of cells. Because cancer cells reproduce more quickly than normal cells, they are targeted by the medication.

So, I personally suggest this drug in your case for adenocarcinoma with metastasis, this drug with combination of other adjuvant like Irinotecan increases the survival rate definitely and it is clinically proved.

Hope this will help you.

And I am ready for the future follow ups.

REGARDS.

Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. Puneet Maheshwari

ENT Specialist

Practicing since :2008

Answered : 661 Questions

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How Effective Is Temodal Chemotherapy For Adenoid Cystic Carcinoma?

Hi,

Thanks for the query,

I have gone through the history, Adenoid cystic carcinoma is a malignant tumor, that metastasizes.

Let me tell you about the TEMODAL chemotherapy.

#Temodal capsule contains temozolomide.

#TEMODAL Capsules are indicated in treatment of patients with reccurent malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma, or any fast growing malignant tumor.

#Therapy can be continued until disease progression stops.

#Temodal should be administered in the fasting state. Antiemetic therapy may be administered prior to or following administration of Temodal.

If vomiting occurs after the dose is administered a second dose should not be administered that day.

EFFICACY OF TEMODAL---

#Use of TEMODAL in combination with other alkylating agents may increase the likelihood of myelosuppression.

#Clinical data suggests it prolongs the progression-free period and overall survival.

#Temozolomide prevents the growth of cancer cells by interfering with the genetic material (DNA) that is necessary for reproduction of cells. Because cancer cells reproduce more quickly than normal cells, they are targeted by the medication.

So, I personally suggest this drug in your case for adenocarcinoma with metastasis, this drug with combination of other adjuvant like Irinotecan increases the survival rate definitely and it is clinically proved.

Hope this will help you.

And I am ready for the future follow ups.

REGARDS.