Brief Answer: Hello, I would love to help! Detailed Answer: Here is what is involved in an endometrial biopsy: 1. You are positioned like you are having a pap smear 2. The cervix is visualized with a speculum 3. The cervix is usually cleaned off 4. A very small "pipelle" is passed through the cervix and into the uterus 5. A very small amount of suction is applied to the end of the pipelle and cells from inside the uterus are collected in the pipelle 6. The pipelle and speculum are removed This usually involves a minimal amount of cramping and a very small amount of spotting. Any woman presenting to the doctor with abnormal bleeding over the age of 40 should have an ultrasound and an endometrial biopsy as part of their workup. Thank you and good luck!

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Brief Answer: Good question.. Detailed Answer: The fluid that is obtained from the uterine cavity is usually a mixture of blood and superficial tissue. It comes out looking like thick fluid with particulate matter. It is actually a very small amount. The specimen of fluid / tissue is put into a container of fluid for preservation while being sent to pathology. So the specimen bottle will just look like a small jar of bloody fluid. I hope that this answers your question!

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