How Long Does Keppra Take To Show Its Effect?

Posted on Mon, 19 Jan 2015

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Mon, 19 Jan 2015 Answered on

Thu, 5 Feb 2015 Last reviewed on

Question : I am on Lexapro 50 mg, Keppra 1750 mg, Klonopin 2 mg and Solian (amisulpride) 100 mg. My psychiatrist decided to give me a higher dosage of Keppra (from 1500 mg to 1750 mg) four days ago and i would like to know how long it takes to work.
Thanks beforehand XXXXXXX

Answered by Dr. Ashok Kumar Choudhary (16 minutes later)

Brief Answer:
It will take around 10-14 days

Detailed Answer:
Dear XXXXXXX
Thanks for using healthcaremagic.

I read your query and understand your concerns posted here in past.

As Levetiracetam(Keppra) is a anti epileptic drug it takes about two weeks to have its complete effect.

It will take around three to four days to achieve a static plasma concentration in your body after dose change and will have required effect on neuronal membranes within a period of two weeks.

If there is no change toward desired status of symptoms dose of Keppra can be adjusted again after two weeks.

At present you need to continue with similar doses for next 10 days and it is hoped that you will get desired effect by that time.

I hope this answers your query.
If you have any other query feel free to write back to me.
Thanks and regards
Dr Ashok Kumar

Above answer was peer-reviewed by : Dr. Raju A.T