How Long Does Serlect Take To Reach Steady Plasma Concentration?

Posted on Mon, 18 Jul 2016

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Mon, 18 Jul 2016 Answered on

Wed, 3 Aug 2016 Last reviewed on

Question : Hi,
I would like to know how long does it take to Serlect (sertindol) to reach steady plasma concentration,
Thanks

Answered by Dr. Alexander H. Sheppe (40 minutes later)

Brief Answer:
Consultation

Detailed Answer:
Hello, and thanks for your question.

The half-life of sertindol is 3 days. It takes 4 half-lives for the drug to reach steady plasma concentration. Therefore, it takes 3*4 = 12 days for the drug to reach steady plasma concentration. It can take up to 6 weeks for the drug to have its intended effect on receptors in the brain and to show full efficacy.

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Above answer was peer-reviewed by : Dr. Nagamani Ng