How Significant Are The Absolute And Relative Nucleated Red Blood
 
                                    
                                    
                                          
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                                           Fri, 27 Dec 2019
                                           
                                        
                                        
                                        
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                                                Fri, 27 Dec 2019
                                                
                                            
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                                            Question : How significant are the absolute and relative nucleated red blood cell counts in management of sickle cell crisis? Do they influence treatment decisions?
                            
                                    Brief Answer:
Not usually
Detailed Answer:
Hi
Thanks for your query.
Nucleated RBCs signify hemolysis. They have no role in pathogenesis of sickle cell crisis, which is due wedging of capillaries by sickle cells.
Hence we need not target them in management of sickle cell crisis.
Hope this helps.
Regards
                                    
                            Not usually
Detailed Answer:
Hi
Thanks for your query.
Nucleated RBCs signify hemolysis. They have no role in pathogenesis of sickle cell crisis, which is due wedging of capillaries by sickle cells.
Hence we need not target them in management of sickle cell crisis.
Hope this helps.
Regards
 Above answer was peer-reviewed by :
                              
                            
                                  
                                      Dr. Vaishalee Punj
                                  
                              
                                         
 
                                    
                                    
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