I Am On Trazodone, Oxycodone And Gabapentin- What Are Interactions?

Posted on Mon, 12 Aug 2019

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Mon, 12 Aug 2019 Answered on

Last reviewed on

Question : I am on trazodone, oxycodone and gabapentin- what are interactions?

Follow up: Dr. Dr. Michelle Gibson (16 minutes later)

Where is my answer? I am directed to so many screens, don't know how to proceed. This is not acceptable

Answered by Dr. Dr. Michelle Gibson (17 minutes later)

Brief Answer:
sedation, may sometimes affect risk of serotonergic syndrome

Detailed Answer:
HI, thanks for using healthcare magic

According to medscape professional drug interaction checker, increased drowsiness/sedation is the main possible interaction that can occur between trazodone and oxycodone.
There has been a suggestion that opioids can sometimes increase the risk of a condition called serotonergic syndrome when combined with some medications.

This is rare side effect but should also be mentioned.

No other interactions are listed between these medication

There are no interactions listed between gabapentin and either of the other 2 medications

I hope this helps, feel free to ask any other questions

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar