I Had Restylane Filler In My Cheeks Removed With Hylenex

Posted on Thu, 17 Oct 2019

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Thu, 17 Oct 2019 Answered on

Last reviewed on

Question : I had restylane filler in my cheeks removed with hylenex (a form of hylarounidase) and three days later I can barely move my left cheek, it wont contract, and my upper lip on my left side will not move. My smile is lopsided. I had hylenex to my right as well but its not affected. I have seen a neurologist and he said it looks like bells palsy. My MRI of brain and left facial nerve was clear. They put me on prednisone for two weeks, as I am now on day 16 with no improvement at all. My eye is not affected and I can wrinkle my forehead. I dont know whats happening. I am desperate for help. Can hylaronidase products destroy your nerves or muscles? I am so upset and dont know what to do.

Answered by Dr. Suresh Heijebu (4 hours later)

Brief Answer:
Possible muscle spasm

Detailed Answer:
Hello Ma'am

I can certainly understand your concern.

I have worked through your attached query in detail.

In my opinion, it does not look like Bell's palsy as there is no significant improvement with a combination of steroids and antivirals.

This looks like localised muscle spasmodic contractions. It generally advocate Botox injections locally for a significant relief.

Yes, in few sensitive individuals hyaluronic acid products may cause some side effects.

Please check with your physician if he/she shares my view and if can prescribe these medications to you.

Post your further questions if any.

Thank you.

Above answer was peer-reviewed by : Dr. Nagamani Ng