I Just Got Blood Work On 10/13/20 That Showed Smooth Muscle

Posted on Sat, 24 Oct 2020

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sat, 24 Oct 2020 Answered on

Tue, 27 May 2025 Last reviewed on

Question : I just got blood work on 10/13/20 that showed Smooth muscle AB screen: Positive and Smooth muscle AB TITER 1:40 H (range is <1:20 titer.

I am scared about what I read it being autoimmune hepatitis, could it be something else as I did have gallbladder Sugery removal on 9/14/20. Hepatitis panel blood results all show negative and Mitochondrial ab screen was negative.

My AST was at 251 and ALT 344 on 10/13/20 bloodwork and recent blood work on 10/20/20 show ALT 85 (10-47 normal range) and AST 41 (11-38 normal range) down from last blood work.

I also had bloodwork on 5/6/2020 showing ACTIN (smooth muscle) Antibody (IGG) at <20 with a reference range: <20 NEGATIVE > or = POSITIVE so confused why it’s positive now on 10/13/20 bloodwork.

Answered by Dr. Ramesh Kumar (4 hours later)

Brief Answer:
Need more details.

Detailed Answer:
Hello ,
Have seen your details, dear.

Before answering your query, please let me know:

Why the test has been done?
I mean who suggested you and why?
What are your symptoms at present and why was the test suggested or they were incidental findings?

Waiting for your reply...
Thanks

Above answer was peer-reviewed by : Dr. Arnab Banerjee

Follow up: Dr. Ramesh Kumar (33 minutes later)

The test where ordered by my gastroenterologist as my liver functions AST, ALT where elevated in the 300’s after my surgery of gallbladder removal on 9/14/20 that was caught on my yearly physical by my primary physician on and wanted to just run a complete work up to be safe.

The elevated liver functions was the only symptoms I was having

Answered by Dr. Ramesh Kumar (38 minutes later)

Brief Answer:
You seem to be fine now.

Detailed Answer:
Hi there,

No significance.
See, in easy language, hepatitis means inflammation of liver cells. Whenever there is inflammation the cells become permeable to enzymes inside it(SGOT, SGPT)...Whether it is Autoimmune/Infective/Any pathology is hepatitis if the liver enzymes would be raised.

Your recent liver enzymes are normal.
Just calm down yourself.
Repeat LFT again after 2 weeks.

Follow a high carbohydrate low fat diet for few weeks.
It's nothing significant and you seem to be fine now.
Regards

Above answer was peer-reviewed by : Dr. Arnab Banerjee

Follow up: Dr. Ramesh Kumar (34 minutes later)

Would you say I have autoimmune hepatitis with the Smooth Muscle AB screen showing positive in labs I uploaded?

Answered by Dr. Ramesh Kumar (32 hours later)

Brief Answer:
Follow up.

Detailed Answer:
Hi again,
Yes as per the test results you have it(Theoretically).
Thanks!

Above answer was peer-reviewed by : Dr. Vaishalee Punj