Is CMIA Method Of HIV Testing Accurate?

Posted on Mon, 18 Aug 2014

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Mon, 18 Aug 2014 Answered on

Fri, 5 Sep 2014 Last reviewed on

Question : My 14 weeks HIV Test report its mentioned it is done by CMIA method. Most people saying CMIA is a DUO test for detecting Antigen and Anbibody both. But my one was only for Antibody. Is it possible? I am attaching the report for your review. Is it a correct report or just a fake one?

Answered by Dr. Praveen G (59 minutes later)

Brief Answer:
Report is conclusive of not having HIV

Detailed Answer:
Hello,
Welcome to Healthcare Magic,

I have gone through your history and the report and it is completely conclusive of No HIV infection.

Chemiluminescent Microparticle Immunoassay(CMIA) is a fourth generation test used to test for HIV1/2. P24 antigen of HIV virus can be detected by this test as early as 10 days. As your test was done at 14 weeks of possible exposure antibody for HIV 1 and 2 are non reactive is conclusive of not having HIV infection.

Your test report is final and 100% alright and just relax don't bother about HIV infection.
Thank you.

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj

Follow up: Dr. Praveen G (1 hour later)

In 4th Generation test it shows antigen rating as well. But in my report it shows only non-reactive antibody test. That is my confusion.Can you please reply my question? It is really making a confusion. I mailed to SRL and not got a suitable reply. If it is a 4th Gen test why Antigen rating not shown? Is it possible to perform only antibody test with CMIA method not antigen?

Answered by Dr. Praveen G (6 hours later)

Brief Answer:
No need for antigen testing

Detailed Answer:
Hello,
Welcome back to Healthcare Magic,

The HIV antigen should be detected at the earliest following your possible exposure. As you have tested after 14 weeks of possible exposure the body immune system would have identified the antigen and produced the antibodies.

So there is no point in detecting HIV antigen so they have tested for HIV 1 and 2, which has turned up Non reactive.

So this test is very sensitive and conclusive that you are not having HIV infection.
Thank you.

Above answer was peer-reviewed by : Dr. Yogesh D

Follow up: Dr. Praveen G (1 hour later)

Can HIV transmits via deep kissing? This incident happened recently. Many doctors and web sites saying its not possible and few saying its possible. Did you see any such cases. After 80 days of that incident i have throat pain with cough generating phlegm ( not much in quantity). Is it related to other STD?

Answered by Dr. Praveen G (16 minutes later)

Brief Answer:
HIV after deep kissing is not possible

Detailed Answer:
Hello,
Welcome back,

Getting HIV following deep kissing is not possible. I have not seen any case of HIV after deep kissing.Your reports suggests there is no HIV infection which is 100% conclusive

The symptoms may be due to upper respiratory tract infection and it is not related to any of the STDs.

Thank you.

Above answer was peer-reviewed by : Dr. Shanthi.E