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Is HIV Test Report Post Six Week Of Exposure,conclusive?

Posted on Thu, 11 Sep 2014

Question: Tested negative on 4th generation HIV test equipment (HIV duo ultra - make VIDAS) on 22th day post exposure; Then Negative result on 4th generation HIV test equipment CMIA make Abbott (P24 antigen & antibody) tested on post 4 and post 5 week and at 6 week after exposure in a reputed lab in XXXXXXX XXXXXXX Also at the same time done on HIV duo ultra post 5 week - result negative. Will be taking post 7 week test soon. Are the tests conclusive? Are there any other definitive test.

Answered by Dr. Bharatesh Devendra Basti (14 minutes later)

Brief Answer:
Conclusive. Free from HIV.

Detailed Answer:
Hi
Thank you for query.
I am Dr Bharatesh D Basti answering query.
You have lots of anxiety with HIV.
The vidas test itself shows negative it is almost accurate at 22 days.it measures p24 and antibody.
Then you have done again tests for antibodies and P24 ag at 6 weeks also. So no hiv antigen or antibody to hiv is found in you
So you are free from HIV and I do not recommend any more tests.
Tests are repeated to relieve the anxiety .
You are becoming more anxious to test.
So allay fear of HIV .relax forget about HIV.
You can get back to me for any clarification .
Thank you
Dr Bharatesh

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Bharatesh Devendra Basti (44 hours later)

Sir thanks for your kind reply. Before I saw your reply I went to post exposure at 7 weak test (antigen antibody test by CMIA - make Abbott) and got non reactive for HIV. But at the same time I did test for Hepatitis B & C test, result are as follows:

1. Anti HCV - non reactive
(Chemiluminescence Micro particle Immunoassay)
No reference range was written on report for Anti HCV

2. Serum HBsAG - non reactive (0.03 IU/ml)
Reference range: non reactive < 0.05 IU/ml
(Chemiluminescence Immunoassay)
The result value 0.03 is very near to 0.05. Should I concern about it and retest or any there is any better test.

Answered by Dr. Bharatesh Devendra Basti (1 hour later)

Brief Answer:
Negative for HIV HBV HCV.so allay fears.

Detailed Answer:

Hi
Thank you for follow up query.
So your tests are negative as expected .So do not worry of HIV, HBV or HCV.
Once it is negative do not worry of the nearness to the normal value.It appears near but it is negative and is nothing to worry.The range for reactive will always be set such that all possibilities of false positive are not there. So do not worry about it at all.
So allay fear of HIV .relax forget about the incident.
Lead a normal safe life.Wish you good health
You can get back to me for any clarifications else please close the discussion and rate.
Thank you
Dr Bharatesh

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Bharatesh Devendra Basti (6 hours later)

Sir, thanks for reply, your comments has increase my mental strength. But I am having a problem for last 3 weeks
1. Feeling feverish and some cold intolerance but temparature at mouth below normal most of time (97.8F to 98.6F) measured daily for 4 to 5 times.
2. Though no clinical fever, but my skin, palm is hot to touch
3. General weakness mostly in leg muscles, mild tingling in thigh muscle
4. Sleepiness and not willing to work
5. NO muscle pain or headache.
6. No swelling of lymph nodes or sore throat
7. Appetites ok
8. No diarrhoea
consulted Endocrinologist but he said it may be viral infection
TC DC HB ESR OK
LIVER FUNCTION TEST OK except total protein just below border line, SGOP SGPT OK
what to do? What further test to do? Is this has any connectionto hiv hepatitis etc

3. Sleepiness and not willing to work
4. No muscle

Answered by Dr. Bharatesh Devendra Basti (13 minutes later)

Brief Answer:
Not hepatitis.

Detailed Answer:
Hi
Thank you for follow up query.
It is good that you have got mental strength.So please forget the episode and do not link symptoms to the episode.
These symptoms may be due to viral or due to anxiety.
As all your tests are normal i do not see any problems related to hepatitis.
So relax take plenty of fluids.Do some yoga meditation and walking.
All these will relive your symptoms and anxiety.
You can get back to me for any clarifications else please close the discussion and rate.
Thank you
Dr Bharatesh

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Bharatesh Devendra Basti (16 hours later)

Sir,
p24 antigen is related to hiv1 only as we know. What about hiv2. Does hiv 2 antibody appears within 6 week or 7 week. I have learned that ther is hiv2 cases in XXXXXXX also. Are the early symptoms and window period same for both?
Regards

Answered by Dr. Bharatesh Devendra Basti (32 minutes later)

Brief Answer:
Can go for RNA-PCR if still anxious.

Detailed Answer:
Hi
Thank you for follow up query.
Yes it tests only for p 24 HIV1 and antibodies of both HIV 1 and 2.
HIV 1 is most common in XXXXXXX HIV2 cases are very rare in India(data not available .one study quotes 0.4% of HIV positive patients) and is not routinely tested in XXXXXXX
If you still have a doubt or anxious of HIV you can go for HIV RNA PCR which will help you to rule out HIV 1 and HIV2 also.
The antibodies appearance may take 3 to 6 months to appear. So not reliable in early weeks of exposure.
HIV2 is known to be milder.
You can get back to me for any clarifications else please close the discussion and rate.
Thank you
Dr Bharatesh

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar