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Is Lorazepam Advisable While Suffering From Autoimmune Hepatitis?

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Posted on Thu, 11 Aug 2016
Question: Can I take loresepam with autoimmune hepatitus
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Answered by Dr. Alexander H. Sheppe (21 minutes later)
Brief Answer:
Consultation

Detailed Answer:
Hello, and thanks for your question.

Lorazepam is a benzodiazepine medication used for treatment of anxiety. It is a short-acting medication that is metabolized through the liver. In someone with autoimmune hepatitis, the liver's function is already compromised, which can lead to a dangerous buildup of benzodiazepine metabolites in the system. I would therefore not take lorazepam. Instead, I would take another medication that is highly effective for anxiety: an antidepressant such as Escitalopram or Sertraline. This is a reasonable alternative.

Please remember to rate and close this answer thread when you are finished and satisfied.

In the future, for continuity of care, I encourage you to contact me directly at my private link below. After you ask a direct question, it would be my pleasure to be your dedicated personal physician on this website. My name is Dr. Sheppe, and I am an XXXXXXX doctor working in New York City at NewYork-Presbyterian Hospital, ranked #1 for Psychiatry in the United States (tinyurl.com/psyrank). For a personalized comprehensive evaluation, treatment recommendations, and individual therapy, ask me at HealthCareMagic at this private link: tinyurl.com/DrSheppeAnswers
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Above answer was peer-reviewed by : Dr. Arnab Banerjee
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Answered by
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Dr. Alexander H. Sheppe

Psychiatrist

Practicing since :2014

Answered : 2236 Questions

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Is Lorazepam Advisable While Suffering From Autoimmune Hepatitis?

Brief Answer: Consultation Detailed Answer: Hello, and thanks for your question. Lorazepam is a benzodiazepine medication used for treatment of anxiety. It is a short-acting medication that is metabolized through the liver. In someone with autoimmune hepatitis, the liver's function is already compromised, which can lead to a dangerous buildup of benzodiazepine metabolites in the system. I would therefore not take lorazepam. Instead, I would take another medication that is highly effective for anxiety: an antidepressant such as Escitalopram or Sertraline. This is a reasonable alternative. Please remember to rate and close this answer thread when you are finished and satisfied. In the future, for continuity of care, I encourage you to contact me directly at my private link below. After you ask a direct question, it would be my pleasure to be your dedicated personal physician on this website. My name is Dr. Sheppe, and I am an XXXXXXX doctor working in New York City at NewYork-Presbyterian Hospital, ranked #1 for Psychiatry in the United States (tinyurl.com/psyrank). For a personalized comprehensive evaluation, treatment recommendations, and individual therapy, ask me at HealthCareMagic at this private link: tinyurl.com/DrSheppeAnswers