Is Naltrexone A Good Medication For Fibromyalgia And How Does It Work?

Posted on Sun, 23 Sep 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sun, 23 Sep 2018 Answered on

Tue, 26 Apr 2022 Last reviewed on

Question : Is naltrexone a good medication for fibromyalgia and how does it work?

Answered by Dr. Dr. Erion Spaho (1 hour later)

Brief Answer:
Low doses of naltrexone may improve fibromyalgia.

Detailed Answer:

Hello,

Yes, Naltrexone is found to improve symptoms of fibromyalgia, but only in low doses, not the normal doses used for opiates addiction.

It works (in low doses) by reducing the brain inflammation that may be caused by chronic diseases.

In other words, low doses of naltrexone are found to suppress the inflammatory response of the microglia.

Discuss with your Doctor if low doses of naltrexone are appropriate in your case.

Hope you found the answer helpful. Let me know if I can assist you further.

Above answer was peer-reviewed by : Dr. Prasad