Is It Correct I Was Diagnosed With Infiltrating Ductal Carcinoma T2N0M0?

Posted on Thu, 21 Apr 2022

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Thu, 21 Apr 2022 Answered on

Tue, 7 Jan 2025 Last reviewed on

Question : I was diagnosed with infiltrating ductal carcinoma T2N0M0, hormone receptor positive in sept 2018.I had 6 cycles of FEC chemotherapy and presently I am on tamoxifen 20mg OD. I am also BRCA 2 positive.Since i have completed 3 years on tamoxifen, my oncologist said that I can try for pregnancy through IVF and also go for PGT test for embryo. I am in dileema regarding pregnancy as i fear of the cancer reoccurence.I met infertility expert and she said it is the best time to try for pregnancy.I had Transvaginal.scan and had 5 follicles in my left and 3 in my right ovary.My uterous and other structures are normal. I am.unable to decide further.Shall i wait for 2 more years for the completion of 5 years or can try now for pregnancy.Kindly guide

Answered by Dr. Olgeta Xhufka (1 hour later)

Brief Answer:
You can try for pregnancy.

Detailed Answer:
Hello,

In theory taking tamoxifen for 5 years may reduce cancer recurrence by 17 %more than taking it for 2 years . About your case you have been using it for three years and all current tests are normal also your carcinoma was T2N0M0 which means it was not spread so you can be in low risk for reocurance.
I think that using tamoxifen for 2 more years and waiting for 2more years will not have good effects on your ovaries quality, follicle qualities.
So as a conclusion you are in perfect time to try for pregnancy.

Hope I have answered the question.
Let me know if I can assist you further.
Thanks.

Above answer was peer-reviewed by : Dr. Dr. Yogesh D

Follow up: Dr. Olgeta Xhufka (2 hours later)

Thank u mam for your valuable guidance.Mam I want to ask that whether I should try for natural conception or shall i proceed for IVF.As i already mentioned that I am BRCA 2 positive too. Is Pregenetic testing for the embryo is necessary? I dont want to got through rigorous cycles of IVF but I am also scared that my child may carry the mutation.I request you to kindly guide me further.

Answered by Dr. Olgeta Xhufka (17 minutes later)

Brief Answer:
Better IVF and PGT

Detailed Answer:
Hello dear and thank you for asking again.
I think that you better undergo IVF and pgt test in order that the embryo can be free of mutations or other conditions and also that IVF can be successful.
As a cancer survival getting pregnant naturally can be more difficult and may have more complications then other pregnancies.
Having IVF and PGT may increase chances of healthy pregnancy and healthy child.
Let me know if I can assist you further.

Above answer was peer-reviewed by : Dr. Dr. Yogesh D

Follow up: Dr. Olgeta Xhufka (2 hours later)

Thanks for advice mam. Are there any chances that i get pregnant in single cycle of IVF.My monthly cycles are regular

Answered by Dr. Olgeta Xhufka (3 hours later)

Brief Answer:
It has good chances

Detailed Answer:
Hello dear and thank you for asking again.
I believe that you have good chances of having successful IVF from first cycle so it is worth to try.

Above answer was peer-reviewed by : Dr. Saisudha Kotla