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Is It Okay To Take Xarelto, Sotolol And Tylenol PM Together?

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Posted on Sat, 28 Apr 2018
Twitter Sat, 28 Apr 2018 Answered on
Twitter Tue, 20 Feb 2024 Last reviewed on
Question : is it ok to take xarelto, sotolol and Tylenol pm together
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Answered by Dr. Bonnie Berger-Durnbaugh (45 minutes later)
Brief Answer:
Skip the Tylenol PM

Detailed Answer:
Hello and welcome,

I put these 3 medications:

Xarelto
Sotalol
Tylenol PM

into the Lexicomp Drug Interactions data base. What came up is that Sotalol and Tylenol PM should not be taken together. The reason for that is that both of these 2 medications have the potential to cause QT prolongation (that's the period of time in the heart cycle from contraction to resting phase) and if you take both, it can compound that potential.

It is ok to take the Xarelto and Sotalol together but skip the Tylenol PM.

If you are interested, I can copy and paste the information about Sotalol and Tylenol PM together.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Bonnie Berger-Durnbaugh

General & Family Physician

Practicing since :1991

Answered : 3133 Questions

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Is It Okay To Take Xarelto, Sotolol And Tylenol PM Together?

Brief Answer: Skip the Tylenol PM Detailed Answer: Hello and welcome, I put these 3 medications: Xarelto Sotalol Tylenol PM into the Lexicomp Drug Interactions data base. What came up is that Sotalol and Tylenol PM should not be taken together. The reason for that is that both of these 2 medications have the potential to cause QT prolongation (that's the period of time in the heart cycle from contraction to resting phase) and if you take both, it can compound that potential. It is ok to take the Xarelto and Sotalol together but skip the Tylenol PM. If you are interested, I can copy and paste the information about Sotalol and Tylenol PM together.