Is It Possible That The Increased Physical Activity Is Altering The Effectiveness Of Seroquel Dose?

Posted on Wed, 5 Feb 2025

Question: My 31 year old son takes 400mg per day of Seroquel for schizophrenia. He has been doing well on it, until recently. Some of his delusional thoughts are surfacing. The happens to have coincided with increased hours at work. He works in light assembly so his physically quite active at work. They have been averaging about 2 hours day additional work each day. Is it possible that the increased physical activity is altering the effectiveness of his dose?

Answered by Dr. Olgeta Xhufka (2 hours later)

Brief Answer:
Possible tolerance or beginning of a relapse.

Detailed Answer:
Hello,

I think he is having a relapse or developing tolerance to seroquel.
Increasing working hours, fatigue, stress may contribute to it.

I think you may need to talk to his Psychiatrist to increase the seroquel dosage.

Hope I have answered the question.
Let me know if I can assist you further.
Thanks.

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Above answer was peer-reviewed by : Dr. Arnab Banerjee