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Is It Safe To Have High Dose Of Progesterone Daily In IVF Pregnancy?

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Posted on Mon, 25 Nov 2013
Twitter Mon, 25 Nov 2013 Answered on
Twitter Sat, 21 Dec 2013 Last reviewed on
Question : I am 7 week pregnant through IVF and my doc. has prescribed susten 400mg(p/ v) 8 times daily as i am progesteron deficient. IS such high dose is safe for my baby. I heard abt neural tubal defect in fetus due to high progesteron level
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Answered by Dr. Sree Gouri SR (54 minutes later)
Brief Answer: Estimation of serum progesterone levels Detailed Answer: Hi, Thanks for the query. Usually during first 12 to 14 weeks of pregnancy, corpus luteum of pregnancy will supply the progesterone. As you are having luteal phase defect, your doctor might have recommend progesterone supplementation. But 3.2gms per day is somewhat higher dose. Higher dose of progesterone may lead to side effects like virilization in the female fetus, genitalambiguity, clitoromegaly etc complications. So, better to go for estimation of serum progesterone levels once. Depending on the result, dose of susten can be adjusted with your doctor's advice. Hope I have answered your query. I will be available to answer followup queries. If you are satisfied with the answer, please give your review at the end of the discussion. Take care.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Sree Gouri SR

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Is It Safe To Have High Dose Of Progesterone Daily In IVF Pregnancy?

Brief Answer: Estimation of serum progesterone levels Detailed Answer: Hi, Thanks for the query. Usually during first 12 to 14 weeks of pregnancy, corpus luteum of pregnancy will supply the progesterone. As you are having luteal phase defect, your doctor might have recommend progesterone supplementation. But 3.2gms per day is somewhat higher dose. Higher dose of progesterone may lead to side effects like virilization in the female fetus, genitalambiguity, clitoromegaly etc complications. So, better to go for estimation of serum progesterone levels once. Depending on the result, dose of susten can be adjusted with your doctor's advice. Hope I have answered your query. I will be available to answer followup queries. If you are satisfied with the answer, please give your review at the end of the discussion. Take care.