Is It Safe To Take Leflunomide And Warfarin Together?
Posted on
Wed, 4 Apr 2018
Medically reviewed by
Ask A Doctor - 24x7 Medical Review Team
Wed, 4 Apr 2018
Answered on
Fri, 16 Jun 2023
Last reviewed on
Question : What is the affect of Leflunomide on Warfarin? Is it safe to take the two together?
Brief Answer:
Ok, but see your primary doctor check if INR is changing.
Detailed Answer:
Hello,
The answer to your question is that Leflunomide can affect Warfarin's effects and can increase or decrease the INR levels. It is not absolutely contraindicated to take the two together, but the INR should be monitored more closely when taking both.
If you have been prescribed these medications from different doctors, be sure that your primary doctor, who checks your INR, knows about this. You may need to have your INR checked in 2-3 days after starting the leflunomide.
Hope I have answered your query.
Regards,
Dr. Bonnie Berger-Durnbaugh, General & Family Physician
Ok, but see your primary doctor check if INR is changing.
Detailed Answer:
Hello,
The answer to your question is that Leflunomide can affect Warfarin's effects and can increase or decrease the INR levels. It is not absolutely contraindicated to take the two together, but the INR should be monitored more closely when taking both.
If you have been prescribed these medications from different doctors, be sure that your primary doctor, who checks your INR, knows about this. You may need to have your INR checked in 2-3 days after starting the leflunomide.
Hope I have answered your query.
Regards,
Dr. Bonnie Berger-Durnbaugh, General & Family Physician
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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