 
                            Is It Safe To Take Leflunomide And Warfarin Together?
 
 
                                    
                                    
                                          
                                               Posted on
                                          
                                            
                                         
                                           Wed, 4 Apr 2018
                                           
                                        
                                        
                                        
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                                             Wed, 4 Apr 2018
                                                
                                            
                                                Answered on
                                                
                                                Wed, 4 Apr 2018
                                                
                                            
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                                             Fri, 16 Jun 2023
                                                
                                                
                                                Last reviewed on
                                                
                                                Fri, 16 Jun 2023
                                                
                                                
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                                            Question : What is the affect of Leflunomide  on Warfarin? Is it safe to take the two together?
                            
                                    Brief Answer:
Ok, but see your primary doctor check if INR is changing.
Detailed Answer:
Hello,
The answer to your question is that Leflunomide can affect Warfarin's effects and can increase or decrease the INR levels. It is not absolutely contraindicated to take the two together, but the INR should be monitored more closely when taking both.
If you have been prescribed these medications from different doctors, be sure that your primary doctor, who checks your INR, knows about this. You may need to have your INR checked in 2-3 days after starting the leflunomide.
Hope I have answered your query.
Regards,
Dr. Bonnie Berger-Durnbaugh, General & Family Physician
                                    
                            Ok, but see your primary doctor check if INR is changing.
Detailed Answer:
Hello,
The answer to your question is that Leflunomide can affect Warfarin's effects and can increase or decrease the INR levels. It is not absolutely contraindicated to take the two together, but the INR should be monitored more closely when taking both.
If you have been prescribed these medications from different doctors, be sure that your primary doctor, who checks your INR, knows about this. You may need to have your INR checked in 2-3 days after starting the leflunomide.
Hope I have answered your query.
Regards,
Dr. Bonnie Berger-Durnbaugh, General & Family Physician
 Above answer was peer-reviewed by :
                              
                            
                                  
                                      Dr. Chakravarthy Mazumdar
                                  
                              
                                          
 
                                    
                                    
                                 
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