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Is It Safe To Undergo Stem Cell Therapy For Liver Cirrhosis?

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Posted on Thu, 26 Dec 2013
Question: My dad have a Child C liver cirrhosis and doctors have recommended liver transplant. I do not find him fit for the transplant because of his age (56) and he his diabetic with some basic kidney issues. We are thinking to undergo stem cell therapy that will actually revive his liver and later we can go for liver transplant if there is a improvement. I want to know what you think about this issue? what should be our steps? if stem cell therapy is recommend then let me know some good hospitals providing this service for liver disease.
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Answered by Dr. Ketan Vagholkar (1 hour later)
Brief Answer: Limited therapeutic options. Detailed Answer: Hi, Thanks for writing in. From the reports which you have provided it appears that the patient will not be able to tolerate the surgical procedure. Bleeding issues, low blood indices, rising bilirubin, borderline renal function are indicators of poor outcome. Though liver transplant is the only hope but the chances of a successful outcome is very less. Past history of encephalopathy following surgery for renal stones is yet another poor prognostic indicator. Stem cell therapy is in the primordial stage as yet. There are no convincing results to support that as a alternative treatment. There are hardly any therapeutic options in the case. Attempting surgery unfortunately would mean just not to leave any stone unturned. I hope this answers your query. Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Ketan Vagholkar (2 hours later)
Thank you doctor for the reply I hope you don't mind telling me some hospitals that do try to regenerate liver through stem cells all over India/ Mumbai. We can't find such institutes. We would like to do whatever we would able to do till the last breath. Note: Naming some stem cells institute would not make you and "health care magic" liable of anything from our side. We would like to visit them as our last hope and as a human being it would be great if you can name them. I take full responsibility. Thank you
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Answered by Dr. Ketan Vagholkar (16 hours later)
Brief Answer: Tata,Bombay and Hinduja hospital Detailed Answer: Hi, Thanks for the feedback. I cannot imagine the stress which you are undergoing. As of Mumbai the only place where you can reliably inquire is Tata Memorial Hospital followed by Bombay Hospital and Hinduja. The problem with stem cell is that it is much in the formative stages. As a result hospitals are not directly declaring their individual success rates. However I would surely research the places and let you know if there are places where this treatment is being successfully done. Internationally both in Europe and even in USA trials are still going on . Hence there are no confirmatory reports regarding the results of this therapy. Regards
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Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Ketan Vagholkar

Gastroenterologist, Surgical

Practicing since :1989

Answered : 883 Questions

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Is It Safe To Undergo Stem Cell Therapy For Liver Cirrhosis?

Brief Answer: Limited therapeutic options. Detailed Answer: Hi, Thanks for writing in. From the reports which you have provided it appears that the patient will not be able to tolerate the surgical procedure. Bleeding issues, low blood indices, rising bilirubin, borderline renal function are indicators of poor outcome. Though liver transplant is the only hope but the chances of a successful outcome is very less. Past history of encephalopathy following surgery for renal stones is yet another poor prognostic indicator. Stem cell therapy is in the primordial stage as yet. There are no convincing results to support that as a alternative treatment. There are hardly any therapeutic options in the case. Attempting surgery unfortunately would mean just not to leave any stone unturned. I hope this answers your query. Regards