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Is Qualitative RNA PCR HIV Test Done One Week Post Exposure Conclusive?
Brief Answer:
You are free from HIV 1 infection beyond any doubt.
Detailed Answer:
Hi,
Welcome to HCM.
Thanks for posting your query.
You had the qualitative RNA PCR to detect the presence of HIV 1 infection. Even though it can detect the presence of infection as early as one week, the test becomes more conclusive by 4 weeks. You had a nonreactive RNA PCR 29 days after the exposure. So it can be considered as more confirmatory and conclusive. So you are free from HIV 1 infection.
I had not come across any case became sero-converted after a 4 weeks nonreactive RNA PCR test for HIV either in my practice of 25 years with HIV patients or in any other publications from the reputed journals or conferences. Nothing to worry.
Dr S.Murugan
You are free from HIV 1 infection beyond any doubt.
Detailed Answer:
Hi,
Welcome to HCM.
Thanks for posting your query.
You had the qualitative RNA PCR to detect the presence of HIV 1 infection. Even though it can detect the presence of infection as early as one week, the test becomes more conclusive by 4 weeks. You had a nonreactive RNA PCR 29 days after the exposure. So it can be considered as more confirmatory and conclusive. So you are free from HIV 1 infection.
I had not come across any case became sero-converted after a 4 weeks nonreactive RNA PCR test for HIV either in my practice of 25 years with HIV patients or in any other publications from the reputed journals or conferences. Nothing to worry.
Dr S.Murugan
Above answer was peer-reviewed by :
Dr. Raju A.T
Brief Answer:
Unlikely
Detailed Answer:
Hi,
Welcome back.
Sorry.
Your 14 days RNA PCR is negative. ok.
I have not come across any such incidence so far (that a 14 days negative with HIV RNA PCR to become sero-converted afterwards) in my practice.
Dr S.Murugan
Unlikely
Detailed Answer:
Hi,
Welcome back.
Sorry.
Your 14 days RNA PCR is negative. ok.
I have not come across any such incidence so far (that a 14 days negative with HIV RNA PCR to become sero-converted afterwards) in my practice.
Dr S.Murugan
Above answer was peer-reviewed by :
Dr. Sonia Raina
You keep calling it a PCR when it is actually a TMA Transcription- Mediated Amplification (TMA) ..., is there any difference or does it change your opinion?
Brief Answer:
Basic principle is to detect the RNA of HIV in all molecular technologies.
Detailed Answer:
Hi,
Welcome back.
All these tests are basically detecting the RNA of HIV, through nucleic acid amplification technology. These molecular technology may vary with each products. But the principle is the same.
Here we are doing only the DNA PCR and Qualitative and quantitative RNA PCR tests. Aptima TMA Gen Probe HIV 1 is not available.
But the general principle is the same. Antigen HIV RNA can be detected as early as one week after the infection and Antibody detecting tests will take more than 6-8 weeks to show a reliable results as the HIV antibody takes time to appear in human body in the presence of infection and it is called as window period.
Aptima TMA gen test may use a different approach to detect the RNA (Ribonucleic acid) of HIV.
What I told was from the experience of Real time RNA PCR test and DNA PCR tests only and not with APTIMA RNA TMA Gen Prob HIV 1 test.
Dr S.Murugan
Basic principle is to detect the RNA of HIV in all molecular technologies.
Detailed Answer:
Hi,
Welcome back.
All these tests are basically detecting the RNA of HIV, through nucleic acid amplification technology. These molecular technology may vary with each products. But the principle is the same.
Here we are doing only the DNA PCR and Qualitative and quantitative RNA PCR tests. Aptima TMA Gen Probe HIV 1 is not available.
But the general principle is the same. Antigen HIV RNA can be detected as early as one week after the infection and Antibody detecting tests will take more than 6-8 weeks to show a reliable results as the HIV antibody takes time to appear in human body in the presence of infection and it is called as window period.
Aptima TMA gen test may use a different approach to detect the RNA (Ribonucleic acid) of HIV.
What I told was from the experience of Real time RNA PCR test and DNA PCR tests only and not with APTIMA RNA TMA Gen Prob HIV 1 test.
Dr S.Murugan
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Above answer was peer-reviewed by :
Dr. Sonia Raina
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