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Is Recovery Possible When Diagnosed With Hepatitis C Genotype 3a And Cirrhosis With Mild Ascites?
Question: Hello doc,
My father is suffering from hepatitis c genotype 3a and decompensated cirrhosis with mild ascites. He is taking dytor plus 5 for ascites. Doctor suggested for sofosbuvir+ribavrin treatment for 48 weeks. I want to know that what are the chances of recovery of liver with this treatment? What is the danger level of his health? Is the treatment safe? His age is 55. Weight is 60kg. I am from XXXXXXX XXXXXXX Please give me your honest suggestions. It would be highly appreciated if you would be XXXXXXX about the chances.
Thanks in advances.
My father is suffering from hepatitis c genotype 3a and decompensated cirrhosis with mild ascites. He is taking dytor plus 5 for ascites. Doctor suggested for sofosbuvir+ribavrin treatment for 48 weeks. I want to know that what are the chances of recovery of liver with this treatment? What is the danger level of his health? Is the treatment safe? His age is 55. Weight is 60kg. I am from XXXXXXX XXXXXXX Please give me your honest suggestions. It would be highly appreciated if you would be XXXXXXX about the chances.
Thanks in advances.
Brief Answer:
60% sustained virological response in 24 weeks
Detailed Answer:
As your father is already decompensated with ascites then over all recovery of liver will be difficult ,but he can attain SVR (sustained virological response) in 12 to 24 weeks with whatever treatment he is on. Sofasbavir is an wonderful drug with very little side effects but ribavarin causes anaemia so you need to regularly follow up with your doctor .And regarding chances it depends on his immune system and complications per se of decompensation like developing varix,severe ascites,coagulopathy, encephalopathy or peritoneal infection .
But if none of the above are present, he will be doing well .
hope this information helps you
thank you.
60% sustained virological response in 24 weeks
Detailed Answer:
As your father is already decompensated with ascites then over all recovery of liver will be difficult ,but he can attain SVR (sustained virological response) in 12 to 24 weeks with whatever treatment he is on. Sofasbavir is an wonderful drug with very little side effects but ribavarin causes anaemia so you need to regularly follow up with your doctor .And regarding chances it depends on his immune system and complications per se of decompensation like developing varix,severe ascites,coagulopathy, encephalopathy or peritoneal infection .
But if none of the above are present, he will be doing well .
hope this information helps you
thank you.
Above answer was peer-reviewed by :
Dr. Shanthi.E
I want to know the survival chances of him. Can you please explain me about SVR because i dont know much about this medical term.
Brief Answer:
sustained virological response- aviremia in 24 weeks of antiviral therapy
Detailed Answer:
Survival chances depends on complication of decompensation which I already discussed earlier , 5 year survival is just 50 % .
you can actually go to your doctor and take an opinion regarding liver transplantation too ,because there are studies showing 5 year survival more then 80% but chances of reinfection is also high .
Thank you
sustained virological response- aviremia in 24 weeks of antiviral therapy
Detailed Answer:
Survival chances depends on complication of decompensation which I already discussed earlier , 5 year survival is just 50 % .
you can actually go to your doctor and take an opinion regarding liver transplantation too ,because there are studies showing 5 year survival more then 80% but chances of reinfection is also high .
Thank you
Above answer was peer-reviewed by :
Dr. Neel Kudchadkar
Thanks doc,
I know there are minor side effects of sofosbuvir+ribavirin. How can we manage side effects? I am asking this because he was a patient of depression. So i am worried about side effects.
I am very much satisfied with your answer doctor. Thanks a lot.
I know there are minor side effects of sofosbuvir+ribavirin. How can we manage side effects? I am asking this because he was a patient of depression. So i am worried about side effects.
I am very much satisfied with your answer doctor. Thanks a lot.
Brief Answer:
sofosbavir and ribavarin don't cause depression
Detailed Answer:
Hi,
sofosbavir and ribavarin dont cause depression ,peg interferon causes depression.
sofosbavir usually causes mild side effects like headache, generalized weakness.
ribavarin causes anemia.
I hope the information is helpfull .
thank you
sofosbavir and ribavarin don't cause depression
Detailed Answer:
Hi,
sofosbavir and ribavarin dont cause depression ,peg interferon causes depression.
sofosbavir usually causes mild side effects like headache, generalized weakness.
ribavarin causes anemia.
I hope the information is helpfull .
thank you
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Above answer was peer-reviewed by :
Dr. Shanthi.E
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