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Is The Pancreatic Acrinar Metaplasia Cause For Concern?

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Posted on Wed, 19 Jun 2024
Question: On my most recent upper endoscopy, the pathology report for biopsy of the lower esophageal junction noted pancreatic acinar metaplasia. Biopsy for the same site was negative for intestinal metaplasia. Is the pancreatic acrinar metaplasia cause for concern? Does it put me at increased risk for Barrett’s, or any other condition? It’s never appeared on any other endoscopy I’ve had. I am 38 and have taken a PPI daily for the past 10 years for GERD. I have attached a copy of the report.
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Answered by Dr. Ramesh Kumar (25 hours later)
Brief Answer:
Please go through detailed answer.

Detailed Answer:
Hello,
Have gone through the query and reports attached by you.
Pancreatic acinar metaplasia just means that some of the glands of pancreas can be seen in gastroesophageal junction.
As your biopsy is normal there is no need to worry.
Pancreatic acinar metaplasia is a normal finding.
So in short there is no need to worry.

It's a common finding in almost 30% of patients in endoscopy.

Please feel free to follow up.
Thanks
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ramesh Kumar

Gastroenterologist

Practicing since :1986

Answered : 2913 Questions

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Is The Pancreatic Acrinar Metaplasia Cause For Concern?

Brief Answer: Please go through detailed answer. Detailed Answer: Hello, Have gone through the query and reports attached by you. Pancreatic acinar metaplasia just means that some of the glands of pancreas can be seen in gastroesophageal junction. As your biopsy is normal there is no need to worry. Pancreatic acinar metaplasia is a normal finding. So in short there is no need to worry. It's a common finding in almost 30% of patients in endoscopy. Please feel free to follow up. Thanks