Is There Any Interaction Of Panadol With Zyprexa And Depakote?

Posted on Mon, 26 May 2014

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Mon, 26 May 2014 Answered on

Thu, 12 Jun 2014 Last reviewed on

Question : Is there any interaction of panadol with zyprexa and depakote?

Answered by Dr. Jonas Sundarakumar (7 hours later)

Brief Answer:
Very minor but non significant interaction.

Detailed Answer:
Hello and welcome to Healthcare Magic. Thanks for your query.

There is a very minor but non-significant interaction between the medication that you have mentioned - Zyprexa (Olanzapine), Depakote (Divalproate) and Pannadol (Acetaminophen).

Depakote can slightly increase the metabolism of Pannadol by the liver. But in persons with normal liver functions, this interaction is insignificant.

So, if you are taking Zyprexa and Depakote, and you don't have any known liver disease, then there is no harm in taking Panadol.

Regards,
Dr. Jonas Sundarakumar MBBS, DPM, MRCPsych(U.K.)
Consultant Psychiatrist

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar