Is There Interaction Between Tramadol And 5-HTP?

Question : I am evaluating the use of 5-htp with Tramadol....my MD put me on Effexor 37.5 mg to treat SE of exemestane (joint and muscle pain, night sweats) ...I took it for a little over a month but had SE of constant headache, nausea, and horrible dreams, so weaned myself off, which took several weeks (even at this low dose) during which I was miserable. I am taking Tramadol 50 mg twice a day for hip, back and hand pain, caused, I believe, by exemestane. I had hoped the 5-HTP might help with the pain and associated mood issues, but see that it may be contraindicated with Tramadol because of effect on serotonin...MD did not think effexor and tramadol together would be a problem because of small dosages of both...but I could not tolerate effexor. I imagine you will tell me to discuss further with my MD, but this box popped up so I thought I'd give it a try:) HX - I am 64 yo, retired RN....had stage 1, grade 3 breast cancer, er+ pr+, lumpectomy in 2/2013, clean margins and sentinel node biopsy clear, 37 radiation treatments.....all follow-up has been ok...some osteopenia that MD says may be age related...cancer markers have been okay.....but I feel like crap with fatigue and especially joint and muscle pain. I walk, attend exercise class and do gentle yoga twice a week. I'd like to be able to do the full 5 years of exemestane, but feel I am trading off on quality of life. Would appreciate any comment on use of Tramodol 50 mg Bid with 5-HTP 100 mg daily......and any other words of wisdom. Thank you for reading this.

In addition to my original question, I am particularly interested in use of supplements, dietary changes, etc. which might positively impact the general feeling of crappiness I have......using, and getting off of, Effexor was a horrible experience. I don't like taking Tramadol, but it does help, so I do. I tried, and could not take Vicodin and Tylenol #3...I felt doped and sick on both. So far the Tramadol has been a life saver, but I don't want to take it forever (maybe just until I finish the exemestane in 3/2018?)....but I understand people often have difficulty getting off of this med, too. ....I do the right dietary stuff (mostly plant based, Mediterranean style diet) In addition to meds mentioned, I take multi vit, calcium 1200 mg, vit D 5000 mg, turmeric capsule, krill oil capsule...all daily.