My Son XXXXXXX Dutta Age 11yr, Having Epilepsy Since 2014,

Posted on Mon, 28 Oct 2019

Question: My son XXXXXXX Dutta age 11yr, Having epilepsy since 2014, Focal followed by generalized. He was treated for ALL with Methotrexate Intrathecally in childhood and gliotic brain MRI say, He has under gone all tests: VEEG, EEG, MRI, Spect, PET CT, XXXXXXX and he is on multiple drug therapy :
1. Tab Eptoin 100 mg BD
2. Tab Levera 1000mg BD
3. Tab MMF 500 mg BD
4. Tab Zenoxa 300 mg BD
5.Tab Fresium 5 mg BD
6. Tab Folvite OD

But of no relief. He has still has seizures 4-5 times day.

He earlier on Valparin, Briviact and many such combination. He was tried for Wysolone for auto immune reason.
Please help me. Multi drug resistant.

Regards
DrRaja Dutta 0000

Answered by Dr. Sudhir Kumar (11 hours later)

Brief Answer:
Your son needs detailed evaluation at a specialised epilepsy center.

Detailed Answer:
Thank you for posting your query.

I am Dr Sudhir Kumar, Neurologist, and I would try my best to help you.

I have noted your son's clinical details. Based on this, I agree with you that it is a case of medically refractory epilepsy.

Giving more than three drugs do not help in further increasing the seizure control rate. Now, he is already on four anti-epileptic drugs and we do not expect a better seizure control by adding more drugs.

So, he should be evaluated in a specialised epilepsy center such as Sree XXXXXXX Institute in XXXXXXX or XXXXXXX New XXXXXXX or NIMHANS, Bengaluru. After which, a decision regarding epilepsy surgery may be taken.

I hope my answer helps. Please get back if you have any follow up queries or if you require any additional information.

Wishing you good health,

Dr Sudhir Kumar MD (Internal Medicine), DM (Neurology) XXXXXXX Consultant Neurologist
Apollo Hospitals, XXXXXXX XXXXXXX
Click on this link to ask me a DIRECT QUERY: http://bit.ly/Dr-Sudhir-kumar
My BLOG: http://bestneurodoctor.blogspot.in

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Sudhir Kumar (14 hours later)

He is seen by Dr XXXXXXX XXXXXXX from XXXXXXX

Answered by Dr. Sudhir Kumar (5 minutes later)

Brief Answer:
She is good.

Detailed Answer:
Thank you for getting back.

Dr XXXXXXX XXXXXXX is good in epilepsy area. Please discuss about the possibility of epilepsy surgery, as medicines have failed to prevent seizure recurrence in your son.

Best wishes,

Dr Sudhir Kumar MD DM

Above answer was peer-reviewed by : Dr. Nagamani Ng